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Anti Microbial Resistance 1st Edition by J Todd Weber ISBN 9783805593236

SKU: BELL-2029244

$ 31.00 ~~$ 45.00~~ (-31%)

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Anti Microbial Resistance 1st Edition by J Todd Weber ISBN 9783805593236 instant download after payment.

Publisher: S. Karger

File Extension: PDF

File size: 1.14 MB

Pages: 185

Author: Medical

ISBN: 9783805593236, 3805593236

Language: English

Year: 2010

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Anti Microbial Resistance 1st Edition by J Todd Weber ISBN 9783805593236 by Medical 9783805593236, 3805593236 instant download after payment.

Anti Microbial Resistance 1st Edition by J Todd Weber - Ebook PDF Instant Download/Delivery: 9783805593236
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ISBN 13: 9783805593236
Author: J Todd Weber

Preventing, controlling and treating drug-resistant infections is one of the major challenges in modern medicine. Antimicrobial Resistance goes beyond simple definitions and microbiological data to fully explore this rapidly changing area, describing evidence for effective interventions, costs, treatment strategies and directions for future research. Each chapter provides essential background and examines the evidence for an important aspect of prevention and control, treatment strategy or policy decision. Prevention and control strategies are analyzed for inappropriate antimicrobial use, fluoroquinolone-resistant organisms, health-care associated infections and parasitic diseases. Furthermore, treatment strategies for changing resistance patterns are explored for community-acquired pneumonia during an influenza pandemic and infections with community-associated MRSA, extended-spectrum beta-lactamase producing organisms and fungi. Data for policy making are presented in articles that detail the costs of antimicrobial-resistant infections in healthcare settings and the threat of resistance with the introduction of antiretroviral therapy for large populations in the developing world. These reviews show where interventions, surveillance and research will be most useful in the future. Antimicrobial Resistance is an invaluable contribution for infectious disease physicians and public health officials who are interested in the prevention of antimicrobial-resistant infections.

Anti Microbial Resistance 1st Table of contents:

Part I: Fundamentals of Antimicrobial Resistance

Chapter 1: History of Antimicrobial Agents and the Emergence of Resistance
- (Discovery of antibiotics, early successes, and the first signs of resistance.)
Chapter 2: Mechanisms of Antimicrobial Resistance in Bacteria
- (Enzymatic inactivation, target modification, efflux pumps, reduced permeability, biofilm formation.)
Chapter 3: Mechanisms of Resistance in Fungi, Viruses, and Parasites
- (Specific resistance mechanisms relevant to antifungals, antivirals, and antiparasitics.)
Chapter 4: Genetics and Evolution of Resistance
- (Horizontal gene transfer, mobile genetic elements, mutations, selection pressure.)
Chapter 5: Antimicrobial Susceptibility Testing (AST) and Surveillance
- (Phenotypic and genotypic methods for resistance detection, global surveillance networks.)

Part II: Epidemiology and Global Burden of AMR

Chapter 6: Global Epidemiology of Antimicrobial Resistance
- (Prevalence, incidence, geographic distribution of resistant pathogens.)
Chapter 7: Clinical Impact of AMR: Morbidity, Mortality, and Healthcare Costs
- (Difficult-to-treat infections, longer hospital stays, increased healthcare expenditure.)
Chapter 8: The "One Health" Approach to AMR
- (Interconnections between human, animal, and environmental health in AMR spread.)
Chapter 9: AMR in Food Production and Agriculture
- (Use of antimicrobials in livestock, aquaculture, and crops; resistance transfer.)
Chapter 10: Environmental Reservoirs and Transmission of AMR
- (Wastewater, soil, natural ecosystems as sources and pathways of resistance genes.)

Part III: Specific Resistant Pathogens and Challenges

Chapter 11: Methicillin-Resistant Staphylococcus aureus (MRSA)
- (Epidemiology, mechanisms, clinical management.)
Chapter 12: Carbapenem-Resistant Enterobacteriaceae (CRE)
- (Mechanisms of carbapenemase production, clinical challenges.)
Chapter 13: Multidrug-Resistant Mycobacterium tuberculosis
- (MDR-TB, XDR-TB, diagnostic and treatment challenges.)
Chapter 14: Drug-Resistant Neisseria gonorrhoeae
- (Threats to STD control.)
Chapter 15: Antifungal Resistance (e.g., Candida auris, Aspergillus fumigatus)
- (Emerging resistant fungal pathogens.)
Chapter 16: Antiviral Resistance (e.g., HIV, Influenza)
- (Mechanisms and impact of resistance to antiviral drugs.)

Part IV: Strategies for Combating AMR

Chapter 17: Antimicrobial Stewardship Programs (ASPs)
- (Hospital and outpatient stewardship, optimizing antimicrobial use.)
Chapter 18: Infection Prevention and Control (IPC)
- (Hygiene, sanitation, vaccination, outbreak management.)
Chapter 19: Research and Development of New Antimicrobials
- (Challenges in drug discovery, novel targets, alternative therapies.)
Chapter 20: Non-Traditional Approaches to AMR
- (Bacteriophage therapy, antimicrobial peptides, probiotics, quorum sensing inhibitors.)
Chapter 21: Vaccines and Immunotherapy for AMR Prevention
- (Role of vaccines in reducing antibiotic use, antibody-based therapies.)
Chapter 22: Policy, Economics, and Global Governance of AMR
- (National action plans, international collaborations, economic incentives for R&D.)
Chapter 23: Public Awareness and Education
- (Communicating the AMR threat to the public and healthcare professionals.)

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Anti Microbial Resistance 1st Edition by J Todd Weber ISBN 9783805593236