Combinatorial Chemistry on Solid Supports 2007th Edition by Stefan Braese ISBN 3540725091 9783540725091 by Nicole Jung, Matthias Wiehn, Stefan Bräse (auth.), Stefan Bräse (eds.) 9783540725091, 3540725091 instant download after payment.

Combinatorial Chemistry on Solid Supports 2007th Edition by Stefan Braese - Ebook PDF Instant Download/Delivery: 3540725091, 9783540725091
Full download Combinatorial Chemistry on Solid Supports 2007th Edition after payment

Product details:

ISBN 10: 3540725091 
ISBN 13: 9783540725091
Author: Stefan Braese

Combinatorial Chemistry on Solid Supports 2007th Table of contents:

• Chapter 1: An Overview of Solid-Phase Synthesis

  • This chapter likely introduces the history of solid-phase synthesis, starting with the pioneering work of Merrifield, and its evolution into a key tool for combinatorial chemistry.

• Chapter 2: Solid Supports for Combinatorial Chemistry

  • Properties of solid supports (resins, beads, etc.)

  • Types of resins (e.g., polystyrene, polyethylene glycol)

  • Functionalization and swelling properties

• Chapter 3: Linkers and Cleavage Strategies

  • Types of linkers (e.g., acid-labile, photolabile)

  • Methods for cleaving molecules from the solid support

  • Orthogonal protection and cleavage

• Chapter 4: Solution-Phase Synthesis on Solid Supports

  • This chapter covers reactions that occur while the molecule is attached to the support.

• Chapter 5: Synthesis of Peptide and Protein Libraries

  • Solid-phase peptide synthesis (SPPS)

  • Synthesis of peptidomimetics

• Chapter 6: Synthesis of Small Molecule Libraries

  • General strategies for creating diverse small molecule libraries.

  • Examples of reactions on solid supports (e.g., heterocycle synthesis).

• Chapter 7: Automation in Solid-Phase Synthesis

  • Manual vs. automated synthesis

  • Automated synthesizers and robotics

  • High-throughput synthesis platforms

• Chapter 8: Encoding and Decoding Strategies

  • Methods to track the identity of compounds in a library (e.g., chemical tags, light-directed synthesis).

  • Deconvolution of encoded libraries.

• Chapter 9: Analytical Methods in Combinatorial Chemistry

  • Techniques for analyzing compounds on the solid support (e.g., FTIR, Magic Angle Spinning NMR).

  • Methods for analyzing cleaved products (e.g., HPLC, Mass Spectrometry).

• Chapter 10: Applications of Solid-Phase Synthesis

  • Use in drug discovery and lead optimization.

  • Applications in material science and catalysis.

People also search for Combinatorial Chemistry on Solid Supports 2007th:

combinatorial chemistry on solid supports
    
combinatorics chemistry
    
combinatorial libraries
    
combinatorial library definition
    
combinatorial chemistry solid phase synthesis

Tags: Stefan Braese, Combinatorial, Chemistry