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Developing Biomarker based Tools for Cancer Screening Diagnosis and Treatment The State of the Science Evaluation Implementation and Economics Workshop Summary 1st Edition by Institute of Medicine, National Cancer Policy Forum, Sharyl Nass, Margie Patlak 0309101344 978-0309101349

  • SKU: BELL-2143558
Developing Biomarker based Tools for Cancer Screening Diagnosis and Treatment The State of the Science Evaluation Implementation and Economics Workshop Summary 1st Edition by Institute of Medicine, National Cancer Policy Forum, Sharyl Nass, Margie Patlak 0309101344 978-0309101349
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Developing Biomarker based Tools for Cancer Screening Diagnosis and Treatment The State of the Science Evaluation Implementation and Economics Workshop Summary 1st Edition by Institute of Medicine, National Cancer Policy Forum, Sharyl Nass, Margie Patlak 0309101344 978-0309101349 instant download after payment.

Publisher: National Academies Press
File Extension: PDF
File size: 1.34 MB
Pages: 113
Author: Margie Patlak Sharyl Nass
ISBN: 0309101344, 9780309101349
Language: English
Year: 2006
Edition: 1

Product desciption

Developing Biomarker based Tools for Cancer Screening Diagnosis and Treatment The State of the Science Evaluation Implementation and Economics Workshop Summary 1st Edition by Institute of Medicine, National Cancer Policy Forum, Sharyl Nass, Margie Patlak 0309101344 978-0309101349 by Margie Patlak Sharyl Nass 0309101344, 9780309101349 instant download after payment.

Developing Biomarker based Tools for Cancer Screening Diagnosis and Treatment The State of the Science Evaluation Implementation and Economics Workshop Summary 1st Edition by Institute of Medicine, National Cancer Policy Forum, Sharyl Nass, Margie Patlak - Ebook PDF Instant Download/Delivery: 0309101344, 978-0309101349

Full download Developing Biomarker based Tools for Cancer Screening Diagnosis and Treatment The State of the Science Evaluation Implementation and Economics Workshop Summary 1st Edition after payment



Product details:

ISBN 10: 0309101344

ISBN 13: 978-0309101349

Author: Institute of Medicine, National Cancer Policy Forum, Sharyl Nass, Margie Patlak

Research has long sought to identify biomarkers that could detect cancer at an early stage, or predict the optimal cancer therapy for specific patients. Fueling interest in this research are recent technological advances in genomics, proteomics, and metabolomics that can enable researchers to capture the molecular fingerprints of specific cancers and fine-tune their classification according to the molecular defects they harbor. The discovery and development of new markers of cancer could potentially improve cancer screening, diagnosis, and treatment. Given the potential impact cancer biomarkers could have on the cost effectiveness of cancer detection and treatment, they could profoundly alter the economic burden of cancer as well.
Despite the promise of cancer biomarkers, few biomarker-based cancer tests have entered the market, and the translation of research findings on cancer biomarkers into clinically useful tests seems to be lagging. This is perhaps not surprising given the technical, financial, regulatory, and social challenges linked to the discovery, development, validation, and incorporation of biomarker tests into clinical practice.

To explore those challenges and ways to overcome them, the National Cancer Policy Forum held the conference "Developing Biomarker-Based Tools for Cancer Screening, Diagnosis and Treatment: The State of the Science, Evaluation, Implementation, and Economics" in Washington, D.C., from March 20 to 22, 2006.

At this conference, experts gave presentations in one of six sessions. In addition, seven small group discussions explored the policy implications surrounding biomarker development and adoption into clinical practice. Developing Biomarker-based Tools for Developing Cancer Screening, Diagnosis, and Treatment: The State of the Science, Evaluation, Implementation, and Economics-Workshop Summary presents the conference proceedings and will be used by an Institute of Medicine (IOM) committee to develop consensus-based recommendations for moving the field of cancer biomarkers forward.

Table of contents:

  1. Genomics, Proteomics, and Metabolomics

  2. Molecular Imaging

  3. Meeting the Technical Challenges of Biomarker Validation and Qualification

  4. Coordinating the Development of Biomarkers and Targeted Therapies

  5. Therapeutics Industry Perspective

  6. Diagnostics Industry Perspective

  7. NCI Perspective

  8. Clinical Investigator Perspective

  9. Biomarker Development and Regulatory Oversight

  10. FDA Critical Path Initiative

  11. Oversight of Diagnostic Tests

  12. Designing Clinical Studies of Biomarkers

  13. Assessment and Adoption of Biomarker-Based Technologies

  14. Federal Programs for Technology Assessment

  15. Insurance Coverage Decisions and Practice Guidelines

  16. CMS Coverage of Biomarkers

  17. Cost-Effectiveness Analysis

  18. Technology Assessment in the Private Sector

  19. Clinical Development Strategies for Biomarker Utilization Discussion

  20. Strategies for Implementing Standardized Biorepositories Discussion

  21. Strategies for Determining Analytic Validity and Clinical Utility of Biomarkers Discussion

  22. Strategies to Develop Biomarkers for Early Detection Discussion

  23. Mechanisms for Developing an Evidence Base Discussion

  24. Evaluation of Evidence in Decision Making Discussion

  25. Incorporating Biomarker Evidence into Clinical Practice Discussion

  26. Acronyms

  27. Glossary

  28. References

  29. Workshop Agenda

  30. Workshop Speakers, Moderators, Invited Discussants, and Participants

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Tags: Institute of Medicine, National Cancer Policy Forum, Developing, Biomarker

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