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Intracondensate Demixing Of Tdp43 Inside Stress Granules Generates Pathological Aggregates Xiao Yan

  • SKU: BELL-238996640
Intracondensate Demixing Of Tdp43 Inside Stress Granules Generates Pathological Aggregates Xiao Yan
$ 35.00 $ 45.00 (-22%)

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Intracondensate Demixing Of Tdp43 Inside Stress Granules Generates Pathological Aggregates Xiao Yan instant download after payment.

Publisher: x
File Extension: PDF
File size: 24.78 MB
Pages: 37
Author: Xiao Yan, David Kuster, Priyesh Mohanty, Jik Nijssen, Karina Pombo-García, Jorge Garcia Morato, Azamat Rizuan, Titus M. Franzmann, Aleksandra Sergeeva, Anh M. Ly, Feilin Liu, Patricia M. Passos, Leah George, Szu-Huan Wang
ISBN: 10.1016/J.CELL.2025.04.039
Language: English
Year: 2025

Product desciption

Intracondensate Demixing Of Tdp43 Inside Stress Granules Generates Pathological Aggregates Xiao Yan by Xiao Yan, David Kuster, Priyesh Mohanty, Jik Nijssen, Karina Pombo-garcía, Jorge Garcia Morato, Azamat Rizuan, Titus M. Franzmann, Aleksandra Sergeeva, Anh M. Ly, Feilin Liu, Patricia M. Passos, Leah George, Szu-huan Wang 10.1016/J.CELL.2025.04.039 instant download after payment.

Stress granules promote TDP-43 aggregation via intra-condensate demixing, a pathway triggered by its up-concentration and oxidation within condensates. Blocking this demixing pathway prevents TDP-43 aggregation, highlighting a potential therapeutic strategy for ALS/FTD diseases.

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