New Insights in the Treatment of Severe Infections in the Multiple Drug Resistant Situation Satellite Symposium to the 11th International 1st Edition by Jr File, T M ISBN 3805578229 9783805578226 by T. M., Jr. File 3805578229, 9783805578226 instant download after payment.
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ISBN 10: 3805578229
ISBN 13: 9783805578226
Author: Jr File, T M
The volume "New Insights in the Treatment of Severe Infections in the Multiple-Drug Resistant Situation: Satellite Symposium to the 11th International Congress on ... March 2004: Proceedings (Chemotherapy)" compiles the cutting-edge discussions and research presented at a pivotal satellite symposium held in conjunction with the 11th International Congress on [likely Infectious Diseases or Antimicrobial Chemotherapy, though the exact full title is not specified in the prompt] in March 2004.
At the turn of the millennium, the escalating crisis of multi-drug resistant (MDR) pathogens was already a formidable challenge to global public health. This collection of proceedings captures the scientific community's focused efforts at that time to grapple with this urgent issue. The symposium brought together leading experts to share novel diagnostic approaches, explore emerging resistance mechanisms, and critically evaluate both existing and experimental therapeutic strategies. With a particular emphasis on severe infections, the papers delve into complex clinical scenarios where conventional antimicrobial treatments are no longer effective, highlighting the critical need for innovative solutions in chemotherapy.
This publication serves as a valuable historical record of the state of antimicrobial resistance and infectious disease management in the early 2000s, offering insights into the foundation upon which subsequent research and clinical practice have been built. It reflects the collaborative spirit and the scientific imperative to address one of the most significant threats to modern medicine.
New Insights in the Treatment of Severe Infections in the Multiple Drug Resistant Situation Satellite Symposium to the 11th International 1st Table of contents:
I. Introduction and Overview
- Welcome and Opening Remarks
- The Global Challenge of Multiple-Drug Resistant (MDR) Infections: An Overview
- Epidemiology and Surveillance of MDR Pathogens in [Relevant Geographic Regions/Context]
- Current Landscape of Antimicrobial Resistance Mechanisms
II. Emerging Threats and Resistance Mechanisms
- Methicillin-Resistant Staphylococcus aureus (MRSA): New Insights into Pathogenesis and Resistance
- Vancomycin-Resistant Enterococci (VRE): Emerging Strains and Treatment Challenges
- Extended-Spectrum Beta-Lactamase (ESBL)-Producing Gram-Negative Bacteria: Epidemiology and Therapeutic Implications
- Carbapenem-Resistant Enterobacteriaceae (CRE): A Growing Crisis
- Multidrug-Resistant Pseudomonas aeruginosa and Acinetobacter baumannii: Novel Resistance Mechanisms
- Resistance in Fungi: Insights into Antifungal Resistance Mechanisms
III. Diagnostic Approaches in MDR Infections
- Rapid Diagnostic Methods for Identifying MDR Pathogens
- Molecular Diagnostics for Resistance Gene Detection
- Pharmacodynamic/Pharmacokinetic Considerations for Optimal Antimicrobial Dosing
- The Role of Clinical Microbiology Laboratories in Guiding Therapy
IV. Novel Therapeutic Strategies and Agents
- New Antimicrobial Agents in Development:
- Novel Beta-Lactams and Beta-Lactamase Inhibitors
- New Fluoroquinolones and Glycopeptides
- Agents Targeting MDR Gram-Negative Bacteria
- Agents Targeting MDR Gram-Positive Bacteria
- Non-Antibiotic Approaches:
- Phage Therapy: Current Status and Future Prospects
- Immunomodulation and Host-Directed Therapies
- Anti-Virulence Strategies
- Optimizing Existing Antimicrobials:
- High-Dose, Prolonged Infusion Strategies
- Combination Therapy for Synergistic Effects
- Therapeutic Drug Monitoring in MDR Infections
V. Management of Specific Severe MDR Infections
- Healthcare-Associated Infections (HAIs) in the MDR Era:
- Ventilator-Associated Pneumonia (VAP) and MDR Pathogens
- Catheter-Related Bloodstream Infections (CRBSI)
- Surgical Site Infections (SSI)
- Community-Acquired MDR Infections:
- Complicated Skin and Soft Tissue Infections (cSSTI)
- Urinary Tract Infections (UTI)
- Intra-abdominal Infections (IAI)
- MDR Infections in Immunocompromised Patients:
- Febrile Neutropenia
- Solid Organ Transplant Recipients
VI. Infection Control and Stewardship in the MDR Context
- Hospital-Wide Infection Prevention and Control Strategies:
- Hand Hygiene Compliance
- Isolation Precautions
- Environmental Decontamination
- Antimicrobial Stewardship Programs:
- Strategies for Optimizing Antimicrobial Use
- Measuring the Impact of Stewardship Interventions
- Global and National Strategies for Combating MDR:
- Policy Initiatives
- International Collaboration and Data Sharing
VII. Future Directions and Challenges
- The Antimicrobial Drug Discovery Pipeline: Gaps and Opportunities
- Economic Burden of MDR Infections
- Public Health Implications and Preparedness
- Addressing the "Silent Pandemic" of Antimicrobial Resistance
- Concluding Remarks and Call to Action
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