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Temporal Coding Carries More Stable Cortical Visual Representations Than Firing Rate Over Time Hanlin Zhu Fei He Pavlo Zolotavin Saumil Patel Andreas S Tolias Lan Luan Chong Xie

  • SKU: BELL-238532630
Temporal Coding Carries More Stable Cortical Visual Representations Than Firing Rate Over Time Hanlin Zhu Fei He Pavlo Zolotavin Saumil Patel Andreas S Tolias Lan Luan Chong Xie
$ 35.00 $ 45.00 (-22%)

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Temporal Coding Carries More Stable Cortical Visual Representations Than Firing Rate Over Time Hanlin Zhu Fei He Pavlo Zolotavin Saumil Patel Andreas S Tolias Lan Luan Chong Xie instant download after payment.

Publisher: x
File Extension: PDF
File size: 33.99 MB
Author: Hanlin Zhu & Fei He & Pavlo Zolotavin & Saumil Patel & Andreas S. Tolias & Lan Luan & Chong Xie
Language: English
Year: 2025

Product desciption

Temporal Coding Carries More Stable Cortical Visual Representations Than Firing Rate Over Time Hanlin Zhu Fei He Pavlo Zolotavin Saumil Patel Andreas S Tolias Lan Luan Chong Xie by Hanlin Zhu & Fei He & Pavlo Zolotavin & Saumil Patel & Andreas S. Tolias & Lan Luan & Chong Xie instant download after payment.

Nature Communications, doi:10.1038/s41467-025-62069-2

Stably representing recurring visual scenes is crucial for behavior. However,previous studies report varying degrees of gradual neural activity changesover time in slow dynamic (1-5 seconds) firing rate code. Here we show thattemporal codes, which capture structures in visually evoked fast (tens ofmilliseconds) spiking patterns, support the stability of visual representations.We tracked the spiking responses of the same visual cortical populations inmale mice for 15 consecutive days using custom-developed, large-scale,ultraflexible electrode arrays. Across various stimuli, neurons exhibited different day-to-day stability in their firing rate-based tuning. The across daystability correlated with tuning reliability. Notably, temporal codes increasedsingle neuron tuning stability, especially for less reliable neurons. Temporalcoding further improved population representation discriminability anddecoding accuracy. The stability of temporal codes was more correlated withnetwork functional connectivity than rate coding. Thus, temporal coding maybe essential in ensuring consistent sensory experiences over time.

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