Activins and Inhibins 1st edition by Gerald Litwack ISBN 0123859617 9780123859617 by Gerald Litwack (eds.) 9780123859617, 0123859611 instant download after payment.

Activins and Inhibins 1st edition by Gerald Litwack - Ebook PDF Instant Download/Delivery: 0123859617 , 9780123859617
Full download Activins and Inhibins 1st edition after payment

Product details:

ISBN 10: 0123859617
ISBN 13: 9780123859617
Author: Gerald Litwack

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms.

Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

Activins and Inhibins 1st Table of contents:

Chapter 1: Activin Receptor-Like Kinase and the Insulin Gene

I. Introduction

II. TGF-beta Family Receptors: ALK

III. Activin Isoforms A, B, and AB

IV. Nodal

V. Insulin Gene Regulation

VI. Conclusion

Acknowledgments

References

Chapter 2: Crystal Structure of Activin Receptor Type IIB Kinase Domain

I. Introduction

II. Type I Receptor Kinase Domain Structures

III. 3D Structure of ActRIIB

IV. Conclusion

References

Chapter 3: Activin/Nodal Signaling and Pluripotency

I. Introduction

II. Conclusion

References

Chapter 4: Intracrine Signaling Mechanisms of Activin A and TGF-beta

I. Common TGF-beta and Activin A Signaling and Target Genes: Focusing on CTGF/CCN2

II. The Early Response to Cellular Stress: Intracellular Activation of TGF-beta

III. Continuous Low-Level Activation of Activin A/TGF-beta Target Genes

IV. Intracrine Signaling: General Aspects

V. Intracrine Signaling of TGF-beta: The Stimulatory Pathway

VI. Intracrine Signaling of TGF-beta: The Inhibitory Pathway

VII. Intracrine Activin A Signaling

VIII. Conclusion

References

Chapter 5: Negative Regulation of Activin Signal Transduction

I. Introduction

II. Extracellular Antagonists

III. Negative Regulation of Activin Receptor Function

IV. Inhibitory Smads

V. Interfering with Smad Function

VI. Negative Regulation of Gene Transcription

VII. Conclusions

Acknowledgments

References

Chapter 6: Antagonism of Activin by Activin Chimeras

I. Introduction

II. The Activin/BMP Receptor System

III. Design of Chimeras

IV. Assessment of Binding and Biological Properties of Chimeras

V. Summary, Conclusions, and Future Directions

Acknowledgments

References

Chapter 7: Activins and Cell Migration

I. Introduction

II. Molecular Mechanism of Activin Signaling Regulated Cell Migration

III. The Role of Activins in the Regulation of Tumor Cell Migration and Metastasis

IV. The Role of Activins in the Modulation of Immune Cell Migration

V. Conclusion and Future Prospective

Acknowledgments

References

Chapter 8: The Synthesis and Secretion of Inhibins

I. Introduction

II. Inhibin Expression and Regulation

III. Expression Profile of Inhibin in Human Tissues

IV. Inhibin Assembly

V. Circulating Inhibin Forms

VI. Concluding Remarks

References

Chapter 9: Multifunctional Roles of Activins in the Brain

I. Introduction

II. Expression Pattern of Activin and Activin Receptor in the Brain

III. Activin Receptor and its Regulatory Proteins

IV. Functions of Activins in the CNS

V. Conclusion and Perspectives

Acknowledgments

References

Chapter 10: The Role of Activin/Nodal and Wnt Signaling in Endoderm Formation

I. Introduction

II. TGFbeta Signaling

III. WNT/beta-Catenin Signaling

IV. Applied Biology

V. Conclusions

Acknowledgments

References

Chapter 11: Activin in Glucose Metabolism

I. Introduction

II. Activin Activity in Insulin-Producing and Insulin-Sensitive Tissues

III. Activin in Adipose Tissue Inflammation

IV. Conclusions and Future Directions

Acknowledgments

References

Chapter 12: Activin in Humoral Immune Responses

I. Introduction

II. Activin A in Th2 Cells

III. Activin A in B Cells

IV. Activin A in Macrophages

V. Activin A in Mast Cells

VI. Conclusions and Future Directions

References

Chapter 13: The Regulation and Functions of Activin and Follistatin in Inflammation and Immunity

I. Introduction

II. Molecular Biology of Activin

III. Production and Regulation of Activin and Follistatin

IV. Activin Actions

V. Conclusions

References

Chapter 14: Feedback Regulation by Inhibins A and B of the Pituitary Secretion of Follicle-Stimulati

I. Introduction

II. Structure, Mechanism of Action, and Function of Inhibins and Activins

III. Inhibins A and B Mediated FSH Suppression in Males and Females

IV. Understanding the Increased Potency of Inhibin B In Vivo and In Vitro

Acknowledgments

References

Chapter 15: Activin A in Nonalcoholic Fatty Liver Disease

I. Introduction

II. Nonalcoholic Fatty Liver Disease

III. Activin A in Liver Biology and Pathology

IV. Activin A in NAFLD

V. Conclusion and Future Perspectives

People also search for Activins and Inhibins 1st:

intra ovarian roles of activins and inhibins

activin and inhibin

activin and inhibin secreted by

activin and inhibin function

activin a and b

Tags: Gerald Litwack, Activins and Inhibins