Advanced Issue Resolution In Safety Pharmacology Mary Jeanne Kallman Michael Pugsley by Mary Jeanne Kallman; Michael Pugsley 9780128122068, 0128122064 instant download after payment.

Advanced Issue Resolution in Safety Pharmacologynot only discusses unique issues that may emerge during the development of new medicines, but also provides detailed insights on how to resolve them. The book employs a valuable strategy that integrates preclinical findings with the clinical resolution of those findings. In addition, it introduces key interdisciplinary topics in an accessible and systematic format. Edited and written by leaders in the field of safety pharmacology, this book considerably advances the discussion on issue resolution topics, thus raising them to the next level of importance by providing scientists with an indispensable resource on solving safety issues.
Focuses on pharmacology issues that result during drug development and provides de-risking techniques and practical advice
Covers a broad selection of topics, including specialized animal models, PBPK modeling, the use of high frequency EEG in problem-solving, drug-induced self-injury, abuse potential liability, biomarkers, imaging, and much more
Focuses on the resolution of these issues in order to better address regulatory expectancies and develop safer, more effective drugs