Advances In Carbohydrate Chemistry And Biochemistry 60 Derek Horton Eds by Derek Horton (eds.) 0120072602, 9780120072606 instant download after payment.

Content: Cover -- Contents -- List of Contributors -- Preface -- Christian Pedersen (1926-2003) -- List of Publications by Christian Pedersen -- Aleksander Wieslaw Zamojski (1929-2004) -- Chemistry of Carbohydrate Aziridines -- Abbreviations -- Introduction -- Methods for the Synthesis of Carbohydrate Aziridines -- Reduction of Azidosulfonates -- Reduction of Cyanosulfonates -- Cyclization of N-Substituted Amino Derivatives -- Cyclization Involving Michael Addition -- Staudinger-Type Cyclization -- Mitsunobu Reaction -- Isomerization of Vicinal Aminooxiranes -- Addition of Nitrenes -- General Properties of Carbohydrate Aziridines -- Reactions of Carbohydrate Aziridines -- General Considerations on Reactivity -- Pyranose Aziridines -- Furanose Aziridines -- Exocyclic Aziridines -- Miscellaneous Reactions of Sugar Aziridines -- References -- Synthesis and Transformation of Glycosyl Azides -- Introduction -- Synthesis of Glycosyl Azides -- Synthesis of 1,2-trans Glycosyl Azides from Glycosyl Halides -- Use of Trimethylsilyl Azide for Synthesis of 1,2-trans-Glycosyl Azides -- Synthesis of 1,2-trans-Glycopyranosyl Azides by Intramolecular Rearrangement -- Synthesis of Glycosyl Azides from Glycosyl Derivatives with an Unprotected Anomeric Center, Employing Phospho-Organic Compounds -- Glycals as Starting Materials for Synthesis of 2-Halo-Substituted Glycosyl Azides -- 1,2-cis Glycosyl Azides -- Transformation of Glycosyl Azides -- Reduction of Glycosyl Azides -- [1,3]-Cycloaddition Reactions of Glycosyl Azides -- Reaction of Glycosyl Azides with Phosphines, Leading to Amines, Amides, and Schiff Bases -- Unprotected and Partially Protected Glycosyl Azides as Starting Materials for N-Glycans -- Oxidation of Glycosyl Azides -- Photochemical and Thermochemical Formations of Glycosyl Azides -- Further Reactions of Glycosyl Azides -- Structural Studies of Glycosyl Azides -- Acknowledgements -- References -- Glycol-Cleavage Oxidation* -- Introduction -- Characteristics of Periodate and Lead Tetraacetate Oxidations -- Mechanisms of Glycol Cleavage -- Some General Properties of Cleavage Reactions: Experimental Methods37 -- Oxidations Other Than Glycol Cleavage: ''Overoxidation'' -- Vicinal Diols Resistant to Glycol Cleavage -- Acyclic Alditols and Cyclitols -- Glycosides and Related Alicyclic Compounds -- Reaction Characteristics; Configurational Relationships -- Dialdehydes -- Reducing Sugars -- Introduction -- Monosaccharides and Partially Substituted Derivatives -- Oligosaccharides -- Polysaccharides -- Oxidation Patterns -- End-Group Analysis -- Fragmentation Analysis -- The Barry and Smith Regioselective Degradation Procedures -- Spectroscopic Methods in Perspective -- Application to Biopolymers -- Acknowledgments -- References -- An Expanding View of Aminoglycoside-Nucleic Acid Recognition -- Introduction -- Early Years -- Mechanism of Action -- Pre-Ribosomal Binding: Cellular Membrane Permeation -- Ribosomal RNA Binding -- Major Issues in Aminoglycoside Therapeutic Applications -- Toxicity -- Combating Toxicity -- Aminoglycoside Resistance -- Fighting Resistance with Aminoglycoside Derivatives -- Experimental Techniques for Probing Aminoglycoside-RNA Interactions -- NMR -- X