Advances in Optical Imaging for Clinical Medicine 1st Edition by Nicusor Iftimia, William R Brugge, Daniel X Hammer ISBN 0470619090 9780470619094 by Nicusor Iftimia, William R. Brugge, Daniel X. Hammer 0470619090 instant download after payment.

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Product details:

ISBN 10: 0470619090 
ISBN 13: 9780470619094
Author: Nicusor Iftimia, William R Brugge, Daniel X Hammer

Advances in Optical Imaging for Clinical Medicine 1st Table of contents:

Part I: Fundamental Principles and Enabling Technologies

• Chapter 1: Introduction to Optical Imaging in Medicine
  • Overview of Medical Imaging Modalities (X-ray, MRI, CT, Ultrasound)
  • The Promise of Optical Imaging: Non-ionizing, High Resolution, Functional Information
  • Basic Principles of Light-Tissue Interaction (Absorption, Scattering, Fluorescence)
  • Historical Perspective and Recent Milestones
• Chapter 2: Light Sources, Detectors, and Optical Components
  • Lasers (Diode, Solid-State, Ultrafast), LEDs, and Supercontinuum Sources
  • Photodetectors (PMTs, CCDs, EMCCDs, SPADs)
  • Fibers, Lenses, Filters, and Other Essential Optics
  • Adaptive Optics for Tissue Penetration
• Chapter 3: Fluorescent Probes and Contrast Agents
  • Endogenous Fluorophores (NAD(P)H, FAD, Collagen, Elastin)
  • Exogenous Dyes and Nanoparticles (Quantum Dots, Gold Nanoparticles, Carbon Dots)
  • Activatable Probes and Biosensors
  • Targeting Strategies for Molecular Imaging

Part II: Established and Emerging Optical Imaging Modalities

• Chapter 4: Optical Coherence Tomography (OCT)
  • Principles of Interferometry and OCT Modalities (Time-Domain, Spectral-Domain, Swept-Source)
  • Doppler OCT for Blood Flow Imaging
  • OCT Angiography (OCTA)
  • Clinical Applications and Case Studies
• Chapter 5: Confocal and Multiphoton Microscopy
  • Principles of Confocal Imaging (Pinhole, Laser Scanning)
  • Two-Photon and Multi-Photon Microscopy for Deep Tissue Imaging
  • Harmonic Generation Microscopy (SHG, THG)
  • In Vivo and Ex Vivo Applications
• Chapter 6: Diffuse Optical Tomography (DOT) and Spectroscopy (DOS)
  • Principles of Light Propagation in Highly Scattering Media
  • Near-Infrared Spectroscopy (NIRS) for Tissue Oxygenation
  • Diffuse Correlation Spectroscopy (DCS) for Blood Flow
  • Reconstruction Algorithms for Tomographic Imaging
• Chapter 7: Photoacoustic (Optoacoustic) Imaging
  • Principles of Photoacoustic Effect
  • Photoacoustic Microscopy (PAM) and Tomography (PAT)
  • Hybrid Modality Advantages (Optical Contrast, Ultrasonic Depth)
  • Clinical Translation and Research Directions
• Chapter 8: Endoscopy and Endomicroscopy
  • Fiber-Optic Imaging Systems
  • Miniature Probes for In Vivo Imaging
  • Confocal Endomicroscopy and OCT Endoscopy
  • Applications in Gastroenterology, Pulmonology, etc.
• Chapter 9: Raman Spectroscopy and Imaging
  • Principles of Raman Scattering
  • Surface-Enhanced Raman Spectroscopy (SERS)
  • Coherent Anti-Stokes Raman Scattering (CARS) Microscopy
  • Label-Free Molecular Fingerprinting in Tissues

Part III: Clinical Applications and Disease-Specific Advances

• Chapter 10: Optical Imaging in Oncology
  • Early Cancer Detection and Diagnosis
  • Image-Guided Biopsy and Surgery
  • Monitoring Treatment Response
  • Specific Applications in Skin, Breast, Colon, Head & Neck Cancers
• Chapter 11: Neuroimaging and Brain Function
  • Functional NIRS for Brain Activation Mapping
  • Optical Imaging of Neural Activity
  • Applications in Stroke, Epilepsy, and Neurodegenerative Diseases
• Chapter 12: Cardiovascular Imaging
  • OCT for Intravascular Plaque Characterization
  • Photoacoustic Imaging for Atherosclerosis
  • Functional Imaging of Cardiac Tissue
• Chapter 13: Ophthalmic and Dermatological Imaging
  • Advanced OCT for Retinal Diseases (AMD, Glaucoma)
  • Microscopy Techniques for Skin Cancer Diagnosis
  • Imaging of Ocular Blood Flow and Structure
• Chapter 14: Other Clinical Applications
  • Orthopedics and Cartilage Imaging
  • Urology and Gynecological Applications
  • Microcirculation and Wound Healing Assessment

Part IV: Data Analysis, Integration, and Future Outlook

• Chapter 15: Image Processing and Quantitative Analysis
  • Image Reconstruction and Enhancement
  • Segmentation, Registration, and Feature Extraction
  • Machine Learning and AI for Image Interpretation
  • Quantitative Biomarker Extraction from Optical Data
• Chapter 16: Multi-Modal and Hybrid Imaging
  • Combining Optical Imaging with Ultrasound, MRI, or PET
  • Synergistic Advantages of Integrated Systems
  • Challenges in Data Fusion and Interpretation
• Chapter 17: Challenges and Limitations of Clinical Translation
  • Depth Penetration vs. Resolution Trade-offs
  • Motion Artifacts and Tissue Heterogeneity
  • Regulatory Pathways and Clinical Trial Design
  • Cost-Effectiveness and Integration into Clinical Workflows
• Chapter 18: The Future of Optical Imaging in Medicine
  • Miniaturization and Wearable Devices
  • AI-Powered Diagnostics and Personalized Medicine
  • Theranostics and Image-Guided Therapies
  • Emerging Technologies and Unforeseen Applications
  • The Road Ahead for Clinical Adoption

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Tags: Nicusor Iftimia, William R Brugge, Daniel X Hammer, Advances, Clinical