Binary Data Analysis Of Randomized Clinical Trials With Noncompliance Kungjong Luiauth by Kung?jong Lui(auth.) 9780470660959, 9781119991618, 0470660953, 1119991617 instant download after payment.

This book provides a systematic and organized approach to analyzing data for RCTs with noncompliance under the most frequently-encountered situations. These include parallel sampling, stratified sampling, cluster sampling, parallel sampling with subsequent missing outcomes, and a series of dependent Bernoulli sampling for repeated measurements. The author provides a comprehensive approach by using contingency tables to illustrate the latent probability structure of observed data. Using real-life examples, computer-simulated data and exercises in each chapter, the book illustrates the underlying theory in an accessible, and easy to understand way.

Key features:

• Consort-flow diagrams and numerical examples are used to illustrate the bias of commonly used approaches, such as, AT analysis, AP analysis and ITT analysis for a RCT with noncompliance.
• Real-life examples are used throughout the book to explain the practical usefulness of test procedures and estimators.
• Each chapter is self-contained, allowing the book to be used as a reference source.
• Includes SAS programs which can be easily modified in calculating the required sample size.

Biostatisticians, clinicians, researchers and data analysts working in pharmaceutical industries will benefit from this book. This text can also be used as supplemental material for a course focusing on clinical statistics or experimental trials in epidemiology, psychology and sociology.Content:
Chapter 1 Randomized Clinical Trials with Noncompliance: Issues, Definitions and Problems of Commonly Used Analyses (pages 1–20):
Chapter 2 Randomized Clinical Trials with Noncompliance under Parallel Groups Design (pages 21–90):
Chapter 3 Randomized Clinical Trials with Noncompliance in Stratified Sampling (pages 91–135):
Chapter 4 Randomized clinical trials with noncompliance under cluster sampling (pages 137–183):
Chapter 5 Randomized Clinical Trials with both Noncompliance and Subsequent Missing Outcomes (pages 185–245):
Chapter 6 Randomized Clinical Trials with Noncompliance in Repeated Binary Measurements (pages 247–287):