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80 reviewsBioinformatics of Genome Regulation and Structure presents selected papers from the Fourth International Conference on Bioinformatics of Genome Regulation and Structure (BGRS), held in Novosibirsk, Russia, in July 2004. The conference was organized by the Laboratory of Theoretical Genetics, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia. The material covers the most recent topics in bioinformatics, including (i) regulatory genomic sequences: databases, knowledge bases, computer analysis, modeling, and recognition; (ii) large-scale genome analysis and functional annotation; (iii) gene structure detection and prediction; (iv) comparative and evolutionary genomics; (v) computer analysis of genome polymorphism and evolution; computer analysis and modeling of transcription, splicing, and translation; structural computational biology: structure- function organization of genomic DNA, RNA, and proteins; (vi) gene networks, signal transduction pathways, and genetically controlled metabolic pathways: databases, knowledge bases, computer analysis, and modeling; principles of organization, operation, and evolution; (vii) data warehousing, knowledge discovery and data mining; and (viii) analysis of basic patterns of genome operation, organization, and evolution.
Bioinformatics of Genome Regulation and Structure will be useful for scientists involved in basic and applied research in the field of experimental and theoretical studies of structure-function organization of genomes, university teachers and students, and mathematicians and biologists.