Biomechanical Effect Of C5c6 Intervertebral Disc Degeneration On The Human Lower Cervical Spine C3c7 A Finite Element Study Rahman Waseem Ur Jiang Wei Zhao Fulin Li Zhijun Wang Guohua Yang Guanghui by Rahman Waseem Ur & Jiang Wei & Zhao Fulin & Li Zhijun & Wang Guohua & Yang Guanghui instant download after payment.

ABSTRACTARTICLE HISTORYThe biomechanical effects of intervertebral discs and facet joints degeneration on the cervicalspine are essential to understanding the mechanisms of spinal disorders to improve pathologicaland clinical treatment. In this study, the biomechanical effects of a progressively degeneratedC5-C6 segment on the human lower cervical spine are determined by a detailed simulation ofintervertebral disc degeneration. A detailed asymmetric three-dimension intact finite elementmodel was developed using computed tomography scan data of the human lower cervicalspine (C3-C7). The intact finite element model was then modified at the C5-C6 segment to buildthree degenerated models, such as mild, moderate, and severe degeneration. The physiologicalcompressive load 73.6 N, and moment 1 Nm were applied at the superior endplate of the vertebra C3, and the inferior endplate of the C7 vertebra was a constraint for all degrees of freedom.Range of motion, maximum von Mises stress in the annulus, intradiscal pressure, and facet jointforce of the degenerated models were computed. With progressive degeneration in the C5-C6segment, the range of motion of degenerated and normal segments decreases in all postures.Intradiscal pressure of the degenerated segment decreases but increases in normal segments ofdegenerated segment C5-C6, and facet joint forces increase at both degenerated and normalsegments. This study emphasizes that the degenerated disc alters the degenerated and normalsegments’ motion and loading patterns. The abnormal increase in facet joint force in the degenerated models threatened to accelerate the degeneration in the normal segments.