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54 reviewsOver the past decade, substantial progress has been made in China in Introductionimproving health-care infrastructure and enacting national policies The CVD burden in Chinafocused on the prevention of cardiovascular disease (CVD) and other Major challenges for CVD non-communicable chronic diseases. Nevertheless, a considerable prevention in Chinagap remains between the national goals for cardiovascular health and Digital health and the burden of CVD in the Chinese population. The rapid advances in AI-facilitated interventionsdigital health-care platforms and the increasing adoption of artifcial Conclusionsintelligence (AI) technologies across various health-care sectors underscore the potential for these innovative approaches to address existing challenges in CVD prevention. In this Review, we summarize the major challenges in implementing preventative strategies and highlight the core obstacles to achieving the national goals for cardiovascular health in China. Furthermore, we discuss the potential value of, and the challenges associated with, digital health-care and AI technology in the implementation of preventative strategies in China and other countries with similar needs.