Cellular Peptidases in Immune Functions and Diseases 2 1st Edition by Jürgen Langner, Siegfried Ansorge 1475786484 978-1475786484 by Uwe Lendeckel, Thilo Kähne, Dagmar Riemann, Klus Neubert, Marco Arndt, Dirk Reinhold (auth.), Jürgen Langner, Siegfried Ansorge (eds.) 0306463830, 9780306463839 instant download after payment.

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ISBN 10: 1475786484

ISBN 13: 978-1475786484

Author: Jürgen Langner, Siegfried Ansorge

Table of contents:

1. Membrane Ectopeptidases with Influence on Immune Functions

2. Review: The Role of Membrane Peptidase in Immune Functions

3. Structure and Function of Aminopeptidase N

4. Modulation of WNT-5A Expression by Actinonin: Linkage of APN to the WNT-Pathway?

5. Enzymatic Activity Is Not A Precondition For The Intracellular Calcium Increase Mediated By mAbs Specific For Aminopeptidase N/CD13

6. Transforming Growth Factor-β Increases the Expression of Aminopeptidase N/CD13 mRNA and Protein in Monocytes and Monocytic Cell Lines

7. Cell-Cell Contact Between Lymphocytes and Fibroblast-Like Synoviocytes Induces Lymphocytic Expression of Aminopeptidase N/CD13 and Results in Lymphocytic Activation

8. Natural Substrates of Dipeptidyl Peptidase IV

9. Relating Structure to Function in the Beta-Propeller Domain of Dipeptidyl Peptidase IV

10. Development of a Tertiary-Structure Model of the C-Terminal Domain of DPP IV

11. Post Proline Cleaving Peptidases Having DP IV Like Enzyme Activity

12. A New Type of Fluorogenic Substrates for Determination of Cellular Dipeptidyl Peptidase IV (DP IV/CD26) Activity

13. Potent Inhibitors of Dipeptidyl Peptidase IV and Their Mechanisms of Inhibition

14. N-Terminal HIV-1 Tat Nonapeptides as Inhibitors of Dipeptidyl Peptidase IV. Conformational Characterization

15. Signal Transduction Events Induced or Affected by Inhibition of the Catalytic Activity of Dipeptidyl Peptidase IV (DP IV, CD26)

16. Specific Inhibitors of Dipeptidyl Peptidase IV Suppress mRNA Expression of DP IV/CD26 and Cytokines

17. Dipeptidyl Peptidase IV in Inflammatory CNS Disease

18. Dipeptidyl Peptidase IV (CD26): Role in T Cell Activation and Autoimmune Disease

19. Effects of Nonapeptides Derived From the N-terminal Structure of Human Immunodeficiency Virus-1 (HIV-1) Tat on Suppression of CD26-Dependent T Cell Growth

20. DNA Synthesis in Cultured Human Keratinocytes and HaCaT Keratinocytes is Reduced by Specific Inhibition of Dipeptidyl Peptidase IV (CD26) Enzymatic Activity

21. Attractin: A Cub-Family Protease Involved in T Cell-Monocyte/Macrophage Interactions

22. Analogs of Glucose-Dependent Insulinotropic Polypeptide With Increased Dipeptidyl Peptidase IV Resistance

23. Dipeptidyl Peptidase IV (DPP IV, CD26) in Patients With Mental Eating Disorders

24. The Membrane-Bound Ectopeptidase CPM as a Marker of Macrophage Maturation in vitro and in vivo

25. Matrix Metalloproteinases (MMP-8, -13 and -14) Interact with the Clotting System and Degrade Fibrinogen and Factor XII (Hageman Factor)

26. The Neprilysin Family in Health and Disease

27. Cellular Endopeptidases: New Cathepsins; Results from Knock-out Mice; Regulatory Aspects

28. Review: Novel Cysteine Proteases of the Papain Family

29. Development and Validation of Homology Models of Human Cathepsins K, S, H, and F

30. The Function of Propeptide Domains of Cysteine Proteinases

31. Human Cathepsins W and F Form a New Subgroup of Cathepsins that is Evolutionarily Separated from the Cathepsin B- and L-Like Cysteine Proteases

32. Cathepsin K Expression in Human Lung

33. Expression of Cathepsins B and L in Human Lung Epithelial Cells is Regulated by Cytokines

34. Functions of Cathepsin K in Bone Resorption

35. Ceramide as an Activator Lipid of Cathepsin D

36. Human Cathepsin X

37. A Novel Proteolytic Mechanism for Termination of the Ca2+ Signalling Evoked by Proteinase-Activated Receptor-1 (PAR-1) in Rat Astrocytes

38. Natural and Synthetic Inhibitors of the Tumor-Associated Serine Protease Urokinase-Type Plasminogen Activator

39. Processing of Interleukin-18 by Human Vascular Smooth Muscle Cells

40. Peptidases and Peptidase Inhibitors in Pathogenesis of Diseases

41. Review: Peptidases and Peptidase Inhibitors in the Pathogenesis of Diseases

42. The Role of Proteolysis in Alzheimer’s Disease

43. Observing Proteases in Living Cells

44. The Role of Cysteine Proteases in Intracellular Pancreatic Serine Protease Activation

45. Peptidases in the Asthmatic Airways

46. Inactivation of Interleukin-6 by Neutrophil Proteases at Sites of Inflammation

47. Antisense Inhibition of Cathepsin B in a Human Osteosarcoma Cell Line

48. Protease-Protease Inhibitor Balance in the Gastric Mucosa

49. The Role of Bacterial and Host Proteinases in Periodontal Disease

50. Multifunctional Role of Proteases in Rheumatic Diseases

51. Evidence of Proteolytic Activation of Transforming Growth Factor-β in Synovial Fluid

52. Matrix Metalloproteinases and TACE Play a Role in the Pathogenesis of Endometriosis

53. Influence of Proliferation, Differentiation and Dedifferentiation Factors on the Expression of the Lysosomal Cysteine Proteinase Cathepsin L (CL) in Thyroid Cancer Cell Lines

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Tags: Jürgen Langner, Siegfried Ansorge, Cellular, Functions