Chitosanbased Systems For Biopharmaceuticals Delivery Targeting And Polymer Therapeutics 2nd Edition Bruno Sarmento by Bruno Sarmento, Jose Das Neves 9780470978320, 0470978325 instant download after payment.

Chitosan-Based Systems for Biopharmaceuticals provides an extensive overview of the application of chitosan and its derivatives in the development and optimisation of biopharmaceuticals. The book is divided in four different parts. Part I discusses general aspects of chitosan and its derivatives, with particular emphasis on issues related to the development of biopharmaceutical chitosan-based systems. Part II deals with the use of chitosan and derivatives in the formulation and delivery of biopharmaceuticals, and focuses on the synergistic effects between chitosan and this particular subset of pharmaceuticals. Part III discusses specific applications of chitosan and its derivatives for biopharmaceutical use. Finally, Part IV presents diverse viewpoints on different issues such as regulatory, manufacturing and toxicological requirements of chitosan and its derivatives related to the development of biopharmaceutical products, as well as their patent status, and clinical application and potential.

Topics covered include:

• chemical and technological advances in chitins and chitosans useful for the formulation of biopharmaceuticals
• physical properties of chitosan and derivatives in sol and gel states
• absorption promotion properties of chitosan and derivatives
• biocompatibility and biodegradation of chitosan and derivatives
• biological and pharmacological activity of chitosan and derivatives
• biological, chemical and physical compatibility of chitosan and biopharmaceuticals
• approaches for functional modification or crosslinking of chitosan
• use of chitosan and derivatives in conventional biopharmaceutical dosage forms
• manufacture techniques of chitosan-based microparticles and nanoparticles for biopharmaceuticals