Clinical, Interventional and Investigational Thrombocardiology 1st Edition by Richard Becker, Robert A Harrington ISBN 0824754190 9780824754198 by Richard Becker, Robert A. Harrington 0824754190, 9780824754198 instant download after payment.

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ISBN 10: 0824754190 
ISBN 13: 9780824754198
Author: Richard Becker, Robert A Harrington

Clinical, Interventional and Investigational Thrombocardiology 1st Table of contents:

Part I: Fundamentals of Thrombosis and Hemostasis

Chapter 1: Platelet Biology and Function

• Platelet Development and Maturation
• Platelet Receptors and Signaling Pathways
• Platelet Activation, Adhesion, and Aggregation
• Role of Platelets in Health and Disease

Chapter 2: The Coagulation Cascade and Fibrinolysis

• Intrinsic and Extrinsic Pathways
• Thrombin Generation and Fibrin Formation
• Natural Anticoagulants and Their Regulation
• Fibrinolysis: Mechanisms and Regulation

Chapter 3: Endothelial Cell Biology and Vascular Wall Interactions

• Endothelial Cell Functions in Thrombosis and Hemostasis
• Role of the Glycocalyx
• Inflammatory Pathways and Thrombosis

Chapter 4: Molecular and Genetic Aspects of Thrombosis

• Genetic Polymorphisms Affecting Coagulation and Platelet Function
• Inherited Thrombophilias

Chapter 5: Laboratory Assessment of Platelet Function and Coagulation

• Standard Coagulation Tests (PT, aPTT, INR)
• Platelet Function Testing (Light Transmission Aggregometry, VerifyNow, etc.)
• Markers of Thrombin Generation and Fibrinolysis
• Specialized Assays for Thrombotic Disorders

Part II: Clinical Thrombosis in Cardiovascular Disease

Chapter 6: Pathophysiology of Atherothrombosis

• Plaque Formation and Rupture
• The Role of Inflammation in Atherothrombosis
• Thrombus Formation in Coronary Artery Disease

Chapter 7: Acute Coronary Syndromes (ACS)

• Unstable Angina, NSTEMI, STEMI
• Role of Thrombosis in ACS Pathogenesis
• Risk Stratification and Diagnosis

Chapter 8: Stroke and Cerebrovascular Disease

• Ischemic Stroke: Thrombotic and Embolic Mechanisms
• Transient Ischemic Attack (TIA)
• Atrial Fibrillation and Stroke Prevention

Chapter 9: Peripheral Artery Disease (PAD) and Venous Thromboembolism (VTE)

• Arterial Thrombosis in PAD
• Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE)
• Pathophysiology and Risk Factors for VTE

Chapter 10: Thrombosis in Heart Failure and Cardiomyopathies

• Hypercoagulability in Heart Failure
• Thromboembolic Complications of Cardiomyopathies

Chapter 11: Thrombosis in Valvular Heart Disease and Prosthetic Valves

• Native Valve Thrombosis
• Thrombosis on Mechanical and Bioprosthetic Valves

Chapter 12: Thrombosis in Pediatric Cardiology

• Congenital Heart Disease and Thrombotic Risk
• Antithrombotic Management in Children

Part III: Interventional Thrombocardiology: Antithrombotic Therapies

Chapter 13: Antiplatelet Agents

• Aspirin: Mechanisms and Clinical Use
• P2Y12 Inhibitors (Clopidogrel, Prasugrel, Ticagrelor): Pharmacokinetics, Pharmacodynamics, and Clinical Trials
• Glycoprotein IIb/IIIa Inhibitors
• Other Antiplatelet Agents (e.g., Vorapaxar)

Chapter 14: Anticoagulants

• Heparins (Unfractionated and Low Molecular Weight Heparins)
• Warfarin and Vitamin K Antagonists
• Direct Oral Anticoagulants (DOACs): Dabigatran, Rivaroxaban, Apixaban, Edoxaban
• Emerging Anticoagulants

Chapter 15: Fibrinolytic Therapy

• Thrombolytic Agents and Their Mechanisms
• Indications and Contraindications in ACS and Stroke
• Management of Bleeding Complications

Chapter 16: Antiplatelet and Anticoagulant Strategies in Acute Coronary Syndromes

• Dual Antiplatelet Therapy (DAPT) in PCI and Medical Management
• Role of Anticoagulation in ACS
• Management of Triple Therapy (DAPT + OAC)

Chapter 17: Antithrombotic Management in Percutaneous Coronary Intervention (PCI)

• Periprocedural Antithrombotic Regimens
• Stent Thrombosis: Mechanisms and Prevention
• Duration of DAPT Post-PCI

Chapter 18: Antithrombotic Management in Atrial Fibrillation

• Stroke Prevention Strategies
• Risk Assessment (CHA2DS2-VASc)
• Selection of Oral Anticoagulants

Chapter 19: Management of Thromboembolism in Peripheral Artery Disease

• Antiplatelet and Anticoagulant Use
• Role of Catheter-Directed Thrombolysis and Thrombectomy

Chapter 20: Management of Venous Thromboembolism (VTE)

• Acute DVT and PE Treatment
• Long-Term Anticoagulation for VTE
• Role of Inferior Vena Cava (IVC) Filters

Part IV: Investigational and Emerging Therapies

Chapter 21: Novel Antiplatelet Targets

• Targeting Thrombin Receptors (PAR-1, etc.)
• Other Platelet Signaling Pathways

Chapter 22: Novel Anticoagulant Strategies

• Factor XI/XIa Inhibitors
• Other Novel Anticoagulant Targets

Chapter 23: Gene Therapy and Cellular Approaches to Thrombosis

• Therapeutic Angiogenesis
• Stem Cell Therapies

Chapter 24: Biomarkers in Thrombocardiology

• Predictive and Prognostic Biomarkers for Thrombotic Risk
• Guiding Antithrombotic Therapy

Chapter 25: Imaging of Thrombosis

• Advanced Imaging Modalities (OCT, IVUS, MRI)
• Functional Imaging of Thrombosis

Chapter 26: Personalized Medicine in Thrombocardiology

• Pharmacogenomics and Antithrombotic Response
• Tailoring Therapy to Individual Patient Risk

Chapter 27: Challenges and Future Directions in Thrombocardiology

• Balancing Bleeding and Ischemic Risk
• Adherence to Therapy
• Global Perspectives on Thrombotic Disease

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