Covid Reference Eng 20216 13 January 2021 6th Edition Bernd Sebastian Kamps by Bernd Sebastian Kamps, Christian Hoffmann 9783942687539, 3942687534 instant download after payment.

0. Top 10 17
1. Epidemiology 19
Hotspots of SARS-CoV-2 Transmission 23
Special Aspects of the Pandemic 38
The SARS-CoV-2 pandemic: Past and Future 47
The 2020 Lockdowns 48
Outlook 52
References 54
2. Transmission 69
Summary 69
Introduction 70
The Virus 70
Person-to-person transmission 72
Routes of Transmission 73
Transmission Event 82
End of Quarantine 95
Prevention 96
Outlook 98
References 99
3. Prevention 117
Introduction 117
Containment or mitigation of COVID-19? 134
Conclusion 135
References 136
4. Virology 153
Introduction 153
References 154
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Kamps – Hoffmann
5. Vaccines 171
Summary 171
Approved SARS-CoV-2 vaccines – An overview 171
Vaccines 179
Vaccine platforms 184
Vaccine candidates in Phase III Trials 186
Immunization fundamentals 192
Questions for the Future 196
Outlook 199
References 201
6. Diagnostic Tests and Procedures 213
Diagnosis 213
Radiology 231
References 234
7. Clinical Presentation 243
Incubation period 243
Asymptomatic cases 244
Symptoms 246
Laboratory findings 257
Clinical classification 261
Outcome 262
Reactivations, reinfections 276
Long-term sequelae/Long COVID-19 277
Outlook 279
References 279
8. Treatment 297
1. Inhibitors of the viral RNA synthesis 299
2. Various antiviral agents 306
3. Monoclonal Antibodies and Convalescent Plasma 309
4. Immunomodulators 315
Other treatments for COVID-19 (with unknown or unproven
mechanisms of action) 323
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Outlook and Recommendations 326
References 327
9. Severe COVID-19 337
Definition and classification 337
Features, course and outcome 337
Spotlight: The situation in a German COVID-19 hospital 339
Special situations in severe COVID-19 341
References 343
10. Comorbidities 347
Hypertension and cardiovascular comorbidities 348
Diabetes mellitus 354
COPD and smoking 356
HIV infection 357
Immunosuppression (other than HIV) 361
Cancer 363
Transplantation 365
Other comorbidities 367
11. Pediatrics 369
SARS-CoV-2 infection in children 369
Epidemiology of COVID-19 in children 370
Natural course and risk factors for complications 371
Pathophysiology and immunopathology 372
Transmission 374
Diagnosis and classification 376
Management 383
References 389
12. The First Eight Months 397
Dezember - March 397
April 413
May 422
June 428
July 439