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0.0
0 reviewsISBN 10: 0878932585
ISBN 13: 9780878932580
Author: Scott F Gilbert
Developmental Biology, Seventh Edition captures the richness, the intellectual excitement, and the wonder of contemporary developmental biology. It is written primarily for undergraduate biology majors but will be useful for introducing graduate students and medical students to developmental biology. In addition to exploring and synthesizing the organismal, cellular, and molecular aspects of animal development, the Seventh Edition expands its coverage of the medical, environmental, and evolutionary aspects of developmental biology.
FEATURES OF THE SEVENTH EDITION
A completely updated text integrates classical developmental biology with contemporary techniques, including the new material on vertebrate limb cell specification, microarrays, RNA interference, microtubular motors, floxed genes, vertebra formation, neural crest differentiation, neural crest specification, heart cell specification, herbicide-induced gonadal disruptions, pancreatic development, digit determination, tadpole deiodinases, insulin-like growth factors, developmental symbioses, and the developmental origins of feathers, jaws, and teeth during evolution.
A new chapter on medical implications of developmental biology The news is full of developmental biology and its medical implications. Therapeutic cloning and cancer therapies, in vitro fertilization, congenital anomalies, and teratogenesis are major concerns not only of scientists but of all citizens. Chapter 21, "Medical Implications of Human Development," brings these topics together and discusses:
* the regulation of fertility
* the identification of genetic defects that affect development
* the identification of teratogenic compounds that affect development
* the identification of factors in the maternal environment which may influence the health of the fetus or the adult
* the realization that cancers can be disruptions of developmental regulation and might be cured through developmental processes
* the attempts to cure developmental diseases (including cancers) through detection, cloning, stem cell therapy, and genetic engineering
* the attempt to cure traumatic and degenerative disease through regeneration.
Part 1. Principles of Development in Biology
Developmental Biology: The Anatomical Tradition
The Questions of Developmental Biology
Anatomical Approaches to Developmental Biology
Comparative Embryology
Evolutionary Embryology
Medical Embryology and Teratology
Mathematical Modeling of Development
Principles of Development: Developmental Anatomy
References
Life Cycles and the Evolution of Developmental Patterns
The Circle of Life: The Stages of Animal Development
The Frog Life Cycle
The Evolution of Developmental Patterns in Unicellular Protists
Multicellularity: The Evolution of Differentiation
Developmental Patterns among the Metazoa
Principles of Development: Life Cycles and Developmental Patterns
References
Principles of Experimental Embryology
Environmental Developmental Biology
The Developmental Mechanics of Cell Specification
Morphogenesis and Cell Adhesion
Principles of Development: Experimental Embryology
References
Genes and Development: Techniques and Ethical Issues
The Embryological Origins of the Gene Theory
Evidence for Genomic Equivalence
Differential Gene Expression
RNA Localization Techniques
Determining the Function of Genes during Development
Identifying the Genes for Human Developmental Anomalies
Principles of Development: Genes and Development
References
The Genetic Core of Development: Differential Gene Expression
Differential Gene Transcription
Methylation Pattern and the Control of Transcription
Transcriptional Regulation of an Entire Chromosome: Dosage Compensation
Differential RNA Processing
Control of Gene Expression at the Level of Translation
Epilogue: Posttranslational Gene Regulation
Principles of Development: Developmental Genetics
References
Cell–Cell Communication in Development
Induction and Competence
Paracrine Factors
Cell Surface Receptors and Signal Transduction Pathways
The Cell Death Pathways
Juxtacrine Signaling
Cross-Talk between Pathways
Coda
Principles of Development: Cell–Cell Communication
References
Part 2. Early Embryonic Development
Fertilization: Beginning a New Organism
Structure of the Gametes
Recognition of Egg and Sperm
Gamete Fusion and the Prevention of Polyspermy
Activation of Egg Metabolism
Fusion of Genetic Material
Rearrangement of the Egg Cytoplasm
Snapshot Summary: Fertilization
References
Early Development in Selected Invertebrates
Early Developmental Processes Overview
Sea Urchin Development
Snail Development
Tunicate Development
Nematode C. elegans Development
References
The Genetics of Axis Specification in Drosophila
Early Drosophila Development
Origins of Anterior–Posterior Polarity
Generation of Dorsal–Ventral Polarity
References
Early Development and Axis Formation in Amphibians
Early Amphibian Development
Axis Formation: The Organizer Phenomenon
References
The Early Development of Vertebrates: Fish, Birds, and Mammals
Early Fish Development
Early Bird Development
Early Mammalian Development
References
Part 3. Later Embryonic Development
The Central Nervous System and the Epidermis
Formation of the Neural Tube
Differentiation of the Neural Tube
Architecture of the CNS
Neuronal Types
Development of the Vertebrate Eye
The Epidermis and Cutaneous Structures
Snapshot Summary: CNS and Epidermis
References
Neural Crest Cells and Axonal Specificity
The Neural Crest
Neuronal Specification and Axonal Specificity
References
Paraxial and Intermediate Mesoderm
The Somites and Their Derivatives
Myogenesis
Osteogenesis
Intermediate Mesoderm
Snapshot Summary
References
Lateral Plate Mesoderm and Endoderm
Lateral Plate Mesoderm
Endoderm
References
Development of the Tetrapod Limb
Formation of the Limb Bud
Proximal–Distal Axis
Anterior–Posterior Axis
Dorsal–Ventral Axis
Coordination among Axes
Cell Death in Digit and Joint Formation
Snapshot Summary: Tetrapod Limb
References
Sex Determination
Chromosomal Sex Determination in Mammals and Drosophila
Environmental Sex Determination
Snapshot Summary: Sex Determination
References
Metamorphosis, Regeneration, and Aging
Metamorphosis: Hormonal Reactivation
Regeneration
Aging: Biology of Senescence
References
The Saga of the Germ Line
Germ Plasm and Primordial Germ Cells
Germ Cell Migration
Meiosis
Spermatogenesis
Oogenesis
Snapshot Summary: The Germ Line
References
Part 4. Ramifications of Developmental Biology
An Overview of Plant Development
Plant Life Cycles
Gamete Production and Fertilization
Embryonic Development
Dormancy and Germination
Vegetative and Reproductive Growth
Senescence
Snapshot Summary: Plant Development
References
Environmental Regulation of Animal Development
Regulation of Normal Development
Environmental Disruption of Development
References
Developmental Mechanisms of Evolutionary Change
“Unity of Type” and “Conditions of Existence”
Hox Genes and Descent with Modification
Homologous Pathways of Development
Modularity and Evolution through Development
Developmental Correlation and Constraints
A New Evolutionary Synthesis
Snapshot Summary: Evolutionary Developmental Biology
References
frontiers in cell and developmental biology
cell and developmental biology
molecular cellular and developmental biology
in vitro cellular & developmental biology plant
pattern formation in developmental biology
Tags: Scott F Gilbert, Developmental, Biology