Diabetic Foot Ulcers Their Characteristics And Trends In Survival Real World Outcomes At A Tertiary Care Facility In India Zachariah Thomas by Zachariah Thomas, Shrirang Kishor Bhurchandi, Bharathi Saravanan, Flory Christina, Ruth Volena, Grace Rebekah, Vasanth Mark Samuel, Pranay Gaikwad, Bobeena Chandy, Anand Samuel, Kripa Elizabeth Cherian, Sheeba Varghese, Felix K. Jebasingh, Nihal Thomas instant download after payment.

Methods: A prospectively maintained database was reviewed to characterize DFU and its association with
amputation and recurrence.

Results: Of 200 patients, 63.5 % were male, the median age was 62 years (Min-Max:40–86), and median BMI was
27.90 kg/m2 (Min-Max:18.5–42.7). Median duration of Diabetes mellitus was 15 years (Min-Max:2–43). Complete healing occurred at a median of three months (Min-Max:0.23–37.62). Amputation for the current ulcer was
required in 43.4 % of individuals. Ulcer recurrence was documented in 42.4 % instances, 66.1 % evolving on the
ipsilateral side. Previous amputation was associated with the risk of subsequent amputation (Adjusted OR-3.08,p-
0.047). Median time to ulcer recurrence was 4.23 years among those with amputation, in contrast to 9.61 years
in those with healing. Cardiovascular death was the commonest cause of mortality, followed by sepsis. At a
median follow up of 6.08 years, mortality at 1,3,5 and 10 years was 2.5 %,2.5 %,8.2 % and 30.9 % respectively
among those who underwent amputation versus 0 %,0 %,10.1 % and 24.5 % respectively for those who achieved
healing.

Conclusions: Patients with DFU in India incur amputations at rates higher than conventionally described. With
previous amputation, subsequent amputation risk triples. Ten-year mortality is 25%–30 %. Underestimates of the
burden of recurrence and mortality are consequential of limited follow-up