Endocrinology Of Aging 1st Emiliano Corpas Marc R Blackman S Mitchell Harman Antonio Ruiztorres by Emiliano Corpas; Marc R. Blackman; S. Mitchell Harman; Antonio Ruiz-torres 9780128196670, 012819667X instant download after payment.

Older persons often express disease differently than do younger adults; as a consequence, clinicians treating
elderly patients need to be aware that both symptoms and laboratory tests require special consideration. This is so both to properly interpret clinical manifestations and to decide on an appropriate therapeutic approach.
Disregarding these differences may lead to significant medical errors with dire consequences.
Many of the physiological age-related changes in metabolism and body composition resemble thosetypically seen with a variety of pathological disturbances in hormone balance. For example, there are decreases
in lean body and muscle mass and in bone density, increases in percent body fat and insulin resistance, and
reductions in resting metabolic rate, energy levels, and libido. These same phenomena are observed in young
adults with deficiencies of growth hormone (GH), sex steroid hormones, and thyroid hormone, as well as with
cortisol excess. To complicate matters further, such changes may also occur in the setting of a variety of
chronic diseases and malnutrition. Furthermore, aging is associated with an increased incidence and
prevalence of a host of illnesses, including endocrine disorders such as autoimmune hypo- and
hyperthyroidism, among others.
Conceptually, it is well understood that endocrine disorders fall into the category of pathophysiology, sothat any signs or symptoms of glandular dysfunction are generally explainable by pathophysiological analysis.
That is, as we age, physiological changes occur that can alter the pathophysiology and therefore the
clinical picture. The main aim of this monograph is to explain the characteristic pathological expressions of
hormonal alterations with advancing age. We hope that the reader will better understand and appreciate those
changes.