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Freeradicalinduced Dna Damage And Its Repair 1st Edition Clemens Von Sonntag

  • SKU: BELL-1127070
Freeradicalinduced Dna Damage And Its Repair 1st Edition Clemens Von Sonntag
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Freeradicalinduced Dna Damage And Its Repair 1st Edition Clemens Von Sonntag instant download after payment.

Publisher: Springer
File Extension: PDF
File size: 13.46 MB
Pages: 528
Author: Clemens von Sonntag
ISBN: 9783642065545, 3642065546
Language: English
Year: 2009
Edition: 1st Edition.

Product desciption

Freeradicalinduced Dna Damage And Its Repair 1st Edition Clemens Von Sonntag by Clemens Von Sonntag 9783642065545, 3642065546 instant download after payment.

Understanding of the molecular basis of DNA damage and its repair has increased dramatically in recent years, and substantial knowledge now exists concerning the products arising from free-radical attack on DNA. Free-radical DNA damage may lead to mutations, cancer, and cell death. Free radicals have various sources, notably ionizing radiation and oxidative stress. In radiotherapy for cancer and with some anticancer drugs, use is made of cell death by excessive DNA damage. The mechanisms leading to products of free-radical attack which have been studied in models and with small double-stranded DNA fragments are discussed in detail, and the basics of the underlying free-radical chemistry are dealt with in separate chapters.

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