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Genetic And Molecular Epidemiology Of Multiple Myeloma 1st Edition Steven Schuster Md

  • SKU: BELL-4290362
Genetic And Molecular Epidemiology Of Multiple Myeloma 1st Edition Steven Schuster Md
$ 31.00 $ 45.00 (-31%)

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Genetic And Molecular Epidemiology Of Multiple Myeloma 1st Edition Steven Schuster Md instant download after payment.

Publisher: Springer-Verlag New York
File Extension: PDF
File size: 1.46 MB
Pages: 125
Author: Steven Schuster M.D., Esteban Braggio Ph.D. (auth.), Suzanne Lentzsch (eds.)
ISBN: 9781461446590, 9781461446606, 1461446597, 1461446600
Language: English
Year: 2013
Edition: 1

Product desciption

Genetic And Molecular Epidemiology Of Multiple Myeloma 1st Edition Steven Schuster Md by Steven Schuster M.d., Esteban Braggio Ph.d. (auth.), Suzanne Lentzsch (eds.) 9781461446590, 9781461446606, 1461446597, 1461446600 instant download after payment.

Multiple myeloma is a plasma cell malignancy characterized by complex heterogenous cytogenetic abnormalities that accounts for 1.4% of all cancers, and approximately 10% of hematologic malignancies. The clinical manifestations of multiple myeloma include lytic bone lesions, cytopenia, hypercalcemia, renal dysfunction, hyperviscosity of the blood, immunodeficiency, and peripheral neuropathy. Based on the clinical and genetic data, probably all cases of multiple myeloma arise from an asymptomatic monoclonal gammopathy of unknown significance. The exact mechanism of the transition from MGUS to overt multiple myeloma is still not well understood. Recent oncogenomic studies have further advanced our understanding of the molecular pathogenesis of multiple myeloma. This book will give a comprehensive overview of the genetic and molecular epidemiology of multiple myeloma in order to get a more refined and conclusive understanding of this disease.

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