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Genetics Fundamentals and applications 1st Edition by Debmalya Barh, H C Srivastava ISBN 818189264X 9788181892645

  • SKU: BELL-2047828
Genetics Fundamentals and applications 1st Edition by Debmalya Barh, H C Srivastava ISBN 818189264X 9788181892645
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Genetics Fundamentals and applications 1st Edition by Debmalya Barh, H C Srivastava ISBN 818189264X 9788181892645 instant download after payment.

Publisher: IBD
File Extension: DJVU
File size: 2.6 MB
Pages: 246
Author: Srivastava H.C., Barh D.
ISBN: 9788181892638, 8181892631
Language: English
Year: 2008

Product desciption

Genetics Fundamentals and applications 1st Edition by Debmalya Barh, H C Srivastava ISBN 818189264X 9788181892645 by Srivastava H.c., Barh D. 9788181892638, 8181892631 instant download after payment.

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Product details:

ISBN 10: 818189264X 
ISBN 13: 9788181892645
Author: Debmalya Barh, H C Srivastava

Genetic is an integrated domain of any advanced field of biology in 21st century. However, successful development of future application will depend on the basic domain knowledge. Genetics: Fundamentals and Applications covers maximum aspects of gentics and it is aimed at readers from multidisciplinary fields of biology. It is an effort to use simple language and examples throughout the book for better understanding of principle of genetics and its application in modern era. Few specific chapters have been incorporated to emphasize the application aspects of genetics in disease pathology and therapeutic areas. Basic principles of genetics (first 19 chapters) have been described in a congnized way with simplest example sets for beginners at under graduate and post graduate level. In contrary, Application part (last 5 chapters) espcially chapters covering cancer genetics, apoptosis and stem cell are written elaborately for post graduate students and researchers in biomedical sciences.

Genetics Fundamentals and applications 1st Table of contents:

Part I: Mendelian Genetics and Chromosomes

  • Chapter 1: Introduction to Genetics
    • What is Genetics?
    • Brief History of Genetics
    • Model Organisms in Genetics
    • Genetics in the Modern World
  • Chapter 2: Mendel's Principles of Inheritance
    • Mendelian Laws: Segregation and Independent Assortment
    • Monohybrid and Dihybrid Crosses
    • Probability in Genetics
    • Pedigree Analysis
  • Chapter 3: Extensions to Mendelian Genetics
    • Incomplete Dominance, Codominance, Multiple Alleles
    • Lethal Alleles
    • Gene Interaction (Epistasis)
    • Pleiotropy and Penetrance/Expressivity
    • Environmental Effects on Gene Expression
  • Chapter 4: Chromosomes and Heredity
    • Cell Cycle: Mitosis and Meiosis
    • Chromosome Theory of Inheritance
    • Sex Determination and Sex-Linked Inheritance
    • X-Inactivation and Dosage Compensation
  • Chapter 5: Linkage, Recombination, and Chromosome Mapping
    • Gene Linkage and Crossing Over
    • Genetic Mapping in Eukaryotes (Two-point and Three-point crosses)
    • Mitotic Recombination

Part II: Molecular Genetics: DNA, RNA, and Protein

  • Chapter 6: The Molecular Structure of Genetic Material
    • DNA as the Genetic Material
    • DNA Structure: The Double Helix
    • DNA Replication
  • Chapter 7: Gene Expression: From DNA to Protein
    • The Central Dogma
    • Transcription: Synthesis of RNA
    • RNA Processing in Eukaryotes
    • Translation: Protein Synthesis and the Genetic Code
  • Chapter 8: Gene Mutation, DNA Repair, and Transposition
    • Types of Mutations
    • Causes of Mutation
    • DNA Repair Mechanisms
    • Transposable Elements

Part III: Regulation of Gene Expression and Genome Organization

  • Chapter 9: Regulation of Gene Expression in Prokaryotes
    • Operons (Lac and Tryptophan operons)
    • Gene Regulation at Different Levels
  • Chapter 10: Regulation of Gene Expression in Eukaryotes
    • Chromatin Structure and Epigenetics
    • Transcriptional Control
    • Post-Transcriptional and Translational Control
    • Small RNAs (miRNAs, siRNAs)
  • Chapter 11: Chromosome Structure and Variation
    • Prokaryotic and Eukaryotic Chromosome Organization
    • Variations in Chromosome Number (Aneuploidy, Polyploidy)
    • Variations in Chromosome Structure (Deletions, Duplications, Inversions, Translocations)

Part IV: Genetics of Organisms and Populations

  • Chapter 12: Genetics of Bacteria and Viruses
    • Bacterial Gene Transfer (Transformation, Conjugation, Transduction)
    • Bacteriophage Genetics
    • Viral Life Cycles and Genetics
  • Chapter 13: Population Genetics
    • Genetic Variation in Populations
    • Hardy-Weinberg Principle
    • Forces of Evolutionary Change (Mutation, Migration, Genetic Drift, Natural Selection)
  • Chapter 14: Quantitative Genetics and Multifactorial Traits
    • Complex Traits and Polygenic Inheritance
    • Heritability
    • Analysis of Quantitative Traits

Part V: Applications of Genetics

  • Chapter 15: Recombinant DNA Technology and Genetic Engineering
    • Cloning Vectors and Restriction Enzymes
    • DNA Libraries
    • PCR (Polymerase Chain Reaction)
    • CRISPR-Cas Systems and Gene Editing
  • Chapter 16: Genomics, Proteomics, and Bioinformatics
    • Genome Sequencing Projects
    • Functional and Comparative Genomics
    • Proteomics and Metabolomics
    • Bioinformatics Tools and Databases
  • Chapter 17: Developmental Genetics
    • Genetic Control of Development
    • Model Systems in Developmental Biology
    • Homeotic Genes
  • Chapter 18: Human Genetics and Genetic Disorders
    • Modes of Inheritance in Humans
    • Chromosomal Disorders
    • Single-Gene Disorders
    • Complex Genetic Disorders
    • Genetic Testing and Counseling
  • Chapter 19: Applied Genetics (Agriculture, Medicine, Forensics, etc.)
    • Plant and Animal Breeding
    • Gene Therapy
    • Pharmacogenomics
    • Forensic Genetics (DNA Fingerprinting)
  • Chapter 20: Genetics and Society: Ethical, Legal, and Social Issues (ELSI)
    • Ethical Considerations in Genetic Engineering
    • Privacy and Genetic Information
    • Genetic Discrimination

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Tags: Debmalya Barh, H C Srivastava, Genetics, Fundamentals

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