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ISBN 10: 0824754727
ISBN 13: 978-1855739550
Author: James Ferrara, H. Joachim Deeg, Kenneth R. Cooke
With detailed contributions from more than 40 leading authorities on the topic, this Third Edition comprehensively explores the immunobiology, pathophysiology, and clinical manifestations of graft-versus-host disease (GVHD)-offering sections revealing the most up-to-date research on immune activation and dysregulation, the pathophysiology of target organ damage, and GVHD prevention and treatment.
The Pathophysiology of Graft-vs.-Host Disease
Animal Models of Graft-vs.-Host Disease
Graft-vs.-Host Disease as a Th1-Type Process: Regulation by Th2-Type Cells
Role of T-Cell Costimulation and Regulatory Cells in Allogeneic Hematopoietic Cell Transplantation
Chemokines and Graft-vs.-Host Disease
Graft-vs.-Leukemia Effects
The Immune System in Graft-vs.-Host Disease: Target and Effector Organ
Pathology and Pathogenesis of Cutaneous Graft-vs.-Host Disease
Graft-vs.-Host Disease of the Liver
Intestinal Graft-vs.-Host Disease
The Pathophysiology of Lung Injury After Hematopoietic Stem Cell Transplantation
Clinical Spectrum of Acute Graft-vs.-Host Disease
Role of Minor Histocompatibility Antigens in the Development of Graft-vs.-Host Disease and Graft-vs.-Leukemia Reactivity
Advances in Tissue Typing and Their Potential Impact on GVHD Incidence and Severity
Immunosuppression and Immunophilin Ligands: Cyclosporin, Tacrolimus, and Sirolimus
Prophylaxis and Treatments of Acute Graft-vs.-Host Disease
Graft Manipulation to Prevent Graft-vs.-Host Disease
Graft-vs.-Host Disease in Nonmyeloablative Transplant
Adoptive Immunotherapy in Stem Cell Transplantation
Clinical Spectrum and Therapeutic Approaches to Chronic Graft-vs.-Host Disease
Recent Advances and Future Directions
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Tags: James Ferrara, H Joachim Deeg, Kenneth R Cooke, Graft vs Host Disease, Third Edition