Highthroughput Screening In Drug Discovery Methods And Principles In Medicinal Chemistry 1st Edition Jrg Hser Editor by Jörg Hüser (editor), Raimund Mannhold, Hugo Kubinyi, Gerd Folkers (series Editors) 3527312838, 9783527312832 instant download after payment.

Content: The basic principles of GRID / Peter Goodford -- Calculation and application of molecular interaction fields / Rebecca C. Wade -- Protein selectivity studies using GRID-MIFs / Thomas Fox -- FLAP: 4-point pharmacophore fingerprints from GRID / Francesca Perrucio ... [et al.] -- The complexity of molecular interaction: molecular shape fingerprints by the PathFinder approach / Iain McLay ... [et al.] -- Alignment-independent descriptors from molecular interaction fields / Manuel Pastor -- 3D-QSAR using the GRID/GOLPE approach / Wolfgang Sippl -- Use of MIF-based VolSurf descriptors in physicochemical and pharmacokinetic studies / Raimund Mannhold ... [et al.] -- Molecular interaction fields in ADME and safety / Giovanni Cianchetta ... [et al.] -- Progress in ADME prediction using GRID-molecular interaction fields / Ismael Zamora ... [et al.] -- Rapid ADME filters for lead discovery / Tudor I. Oprea ... [et al.] -- GRID-derived molecular interaction fields for predicting the site of metabolism in human cytochromes / Gabriele Cruciani ... [et al.]