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Histone Deacetylases Transcriptional Regulation And Other Cellular Functions Cancer Drug Discovery And Development 1st Edition Eric Verdin

  • SKU: BELL-2091240
Histone Deacetylases Transcriptional Regulation And Other Cellular Functions Cancer Drug Discovery And Development 1st Edition Eric Verdin
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Histone Deacetylases Transcriptional Regulation And Other Cellular Functions Cancer Drug Discovery And Development 1st Edition Eric Verdin instant download after payment.

Publisher: Humana Press
File Extension: PDF
File size: 12.14 MB
Pages: 349
Author: Eric Verdin
ISBN: 1588294994
Language: English
Year: 2006
Edition: 1

Product desciption

Histone Deacetylases Transcriptional Regulation And Other Cellular Functions Cancer Drug Discovery And Development 1st Edition Eric Verdin by Eric Verdin 1588294994 instant download after payment.

A panel of leading investigators summarizes and synthesizes the new discoveries in the rapidly evolving field of histone acetylation as a key regulatory mechanism for gene expression. The authors describe what has been learned about these proteins, including the identification of the enzymes, the elucidation of the enzymatic mechanisms of action, and the identification of their substrates and their partners. They also review the structures that have been solved for a number of enzymes-both alone and in complex with small molecule inhibitors-and the biological roles of the several histone deacetylases (HDAC) genes that have been knocked out in mice.

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