Hivassociated Hematological Malignancies 1st Edition Marcus Hentrich by Marcus Hentrich, Stefan K. Barta (eds.) 9783319268552, 9783319268576, 3319268554, 3319268570 instant download after payment.

This book presents a general introduction to and review of HIV-associated hematological malignancies, with a special focus on practical management issues. Each of the relevant malignancies is addressed individually, with an overview of treatment approaches, assessment of evidence regarding their efficacy, and discussion of therapeutic controversies. In addition, careful consideration is paid to issues in molecular and clinical pathology, epidemiological aspects, symptomatology, diagnosis, and risk factors. Separate chapters are devoted to autologous and allogeneic stem cell transplantation and to chemotherapy and interactions with antiretroviral agents. Many of the chapters are written by experts who have been instrumental in shifting the balance for people living with HIV and blood cancers. While two decades ago this diagnosis represented a death sentence, advances in treatment have transformed these cancers into often curable conditions. Nevertheless, optimal treatment of hematological malignancies remains a challenge, particularly in patients with severe immunosuppression. This book will be an invaluable source of information for all practitioners in the fields of clinical hematology and medical oncology and HIV medicine.
本书对HIV相关血液系统恶性肿瘤进行了一般介绍和综述，特别关注实际管理问题。对每种相关恶性肿瘤进行单独处理，概述治疗方法，评估有关其疗效的证据，并讨论治疗争议。此外，还仔细考虑了分子和临床病理学、流行病学方面、症状学、诊断和危险因素方面的问题。单独的章节专门讨论自体和同种异体干细胞移植以及化疗和与抗逆转录病毒药物的相互作用。其中许多章节是由专家撰写的，他们在改变艾滋病毒和血癌感染者的平衡方面发挥了重要作用。虽然二十年前这种诊断代表着死刑，但治疗的进步已经将这些癌症转化为通常可以治愈的疾病。然而，血液系统恶性肿瘤的最佳治疗仍然是一个挑战，特别是在严重免疫抑制患者中。本书将成为临床血液学、肿瘤内科和HIV医学领域所有从业者的宝贵信息来源。