Ideas in Chemistry and Molecular Sciences Where Chemistry Meets Life 1st Edition by Bruno Pignataro ISBN 3527325417 9783527325412 by Bruno Pignataro 3527325417 instant download after payment.

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ISBN 10: 3527325417 
ISBN 13: 9783527325412
Author: Bruno Pignataro

Ideas in Chemistry and Molecular Sciences Where Chemistry Meets Life 1st Table of contents:

Part I: Fundamental Principles at the Interface

• Chapter 1: The Chemical Language of Life: From Atoms to Macromolecules
  • 1.1 Basic Chemical Principles (bonding, intermolecular forces, thermodynamics relevant to biology).
  • 1.2 The Building Blocks of Life (amino acids, nucleotides, sugars, lipids).
  • 1.3 Structure and Function of Biomacromolecules (proteins, nucleic acids, carbohydrates).
  • 1.4 Self-Assembly and Supramolecular Chemistry in Biological Systems.
• Chapter 2: Chemical Energetics and Biological Processes
  • 2.1 Bioenergetics: ATP, Redox Reactions, and Metabolic Pathways.
  • 2.2 Enzyme Catalysis: Chemical Mechanisms and Kinetic Insights.
  • 2.3 Photosynthesis and Respiration: Harnessing and Converting Energy.
• Chapter 3: Water, pH, and Biological Buffering
  • 3.1 The Unique Properties of Water as the Solvent of Life.
  • 3.2 Acid-Base Chemistry in Biological Systems.
  • 3.3 The Role of Buffers in Maintaining Physiological Homeostasis.

Part II: Chemical Biology: Probing and Manipulating Life

• Chapter 4: Chemical Probes for Biological Systems
  • 4.1 Designing and Synthesizing Small Molecule Probes.
  • 4.2 Fluorescent Probes for Imaging and Sensing.
  • 4.3 Activity-Based Protein Profiling (ABPP).
  • 4.4 Click Chemistry in Biological Labeling.
• Chapter 5: Unraveling Biological Mechanisms with Chemistry
  • 5.1 Chemical Genetics: Using Small Molecules to Modulate Protein Function.
  • 5.2 Optogenetics: Light-Control of Biological Processes.
  • 5.3 Dynamic Covalent Chemistry in Biological Systems.
  • 5.4 Studying Protein-Ligand Interactions.
• Chapter 6: Synthetic Biology and Artificial Life
  • 6.1 De Novo Design of Proteins and Enzymes.
  • 6.2 Engineering Metabolic Pathways for Bioproduction.
  • 6.3 Constructing Synthetic Cells and Protocells.
  • 6.4 Designing Artificial Nucleic Acids and Genetic Systems.

Part III: Chemistry for Health and Medicine

• Chapter 7: Principles of Drug Discovery and Medicinal Chemistry
  • 7.1 Target Identification and Validation.
  • 7.2 High-Throughput Screening and Lead Discovery.
  • 7.3 Structure-Activity Relationship (SAR) and Lead Optimization.
  • 7.4 Pharmacokinetics (ADME) and Drug Metabolism.
• Chapter 8: Advanced Therapeutic Modalities
  • 8.1 Biologics: Antibodies, Peptides, and Gene Therapies.
  • 8.2 Nanomedicine: Drug Delivery Systems and Diagnostics.
  • 8.3 Precision Medicine and Personalized Therapeutics.
  • 8.4 Chemical Approaches to Regenerative Medicine.
• Chapter 9: Diagnostics and Biosensors
  • 9.1 Chemical Sensing Technologies for Biomarkers.
  • 9.2 Point-of-Care Diagnostics.
  • 9.3 Imaging Agents for Medical Diagnosis.
  • 9.4 Microfluidics and Lab-on-a-Chip Systems.

Part IV: Bio-Inspired Chemistry and Sustainable Solutions

• Chapter 10: Biomimicry and Bio-Inspired Materials
  • 10.1 Learning from Nature's Designs (e.g., bone, shell, spider silk).
  • 10.2 Self-Healing Materials.
  • 10.3 Smart and Responsive Materials for Biomedical Applications.
• Chapter 11: Green Chemistry and Biotechnology for Sustainability
  • 11.1 Biocatalysis and Enzyme Engineering for Sustainable Synthesis.
  • 11.2 Biofuels and Renewable Energy from Chemical Perspectives.
  • 11.3 Bioremediation and Environmental Chemistry.
  • 11.4 Sustainable Polymer Chemistry.

Part V: Emerging Frontiers and Future Outlook

• Chapter 12: Chemogenomics and Proteomics
  • 12.1 High-Throughput Approaches to Understanding Chemical-Biological Interactions.
  • 12.2 Integrating Chemical Data with Genomic and Proteomic Information.
• Chapter 13: The Role of AI and Machine Learning in Chemical Biology
  • 13.1 Accelerating Drug Discovery and Material Design.
  • 13.2 Predicting Biological Activity and Toxicity.
  • 13.3 Automating Chemical Synthesis and Experimentation.
• Chapter 14: Grand Challenges and Ethical Considerations
  • 14.1 Addressing Global Health Challenges (e.g., antimicrobial resistance, neglected diseases).
  • 14.2 Ethical Implications of Synthetic Biology and Gene Editing.
  • 14.3 The Future Landscape of Chemical and Molecular Sciences.

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Tags: Bruno Pignataro, Chemistry, Molecular