Immunotherapy For Gastrointestinal Cancer 1st Edition David Kerr by David Kerr, Rebecca Johnson (eds.) 9783319430614, 9783319430638, 3319430610, 3319430637 instant download after payment.

This book is about the manipulation of the immune system as a therapeutic approach to gastrointestinal cancer and its clinical applications, exploring therapeutic approaches which might be taken under the broad banner of immunotherapy.
本书是关于操纵免疫系统作为胃肠道癌症的治疗方法及其临床应用，探索了可能在免疫疗法的广泛旗帜下采取的治疗方法。

Starting by introducing concepts of modern immunology, the clinical applications of immunotherapy are then discussed. The reader will learn about the three broad classes of immune therapeutic agents: cell-based treatment; antibody therapy; cytokine application and the key effector cells and mechanisms which might cause tumour rejection. The reverse side of this equation, the genetic and molecular mechanisms which the tumour can use to escape immune control and regulation, is also discussed. Through reviewing the most up-to-date evidence, this volume provides an overview of the important scientific lessons learned from past failure of immunotherapeutics in the clinic and highlights more positive recent data, coupled to practical guidelines for clinical usage.
首先介绍现代免疫学的概念，然后讨论免疫疗法的临床应用。读者将了解三大类免疫治疗剂：基于细胞的治疗;抗体治疗;细胞因子应用和可能导致肿瘤排斥反应的关键效应细胞和机制。这个等式的反面，肿瘤可以用来逃避免疫控制和调节的遗传和分子机制，也被讨论了。通过回顾最新证据，本卷概述了从过去临床免疫治疗失败中吸取的重要科学教训，并强调了更积极的最新数据，以及临床使用的实用指南。

Written by a team of worldwide experts, this is an indispensable guide for medical oncologists, surgical oncologists, radiation therapists, pharmacists, oncology nurse specialists.