Insulin and Related Proteins Structure to Function and Pharmacology 1st Edition by Matthias Federwisch, Markus Leyck Dieken, Pierre De Meyts ISBN 9401739560 9789401739566 by Matthias Federwisch (editor), Markus Leyck Dieken (editor), Pierre De Meyts (editor) 1402006551, 9781402006555 instant download after payment.

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ISBN 10: 9401739560 
ISBN 13: 9789401739566
Author: Matthias Federwisch, Markus Leyck Dieken, Pierre De Meyts

Insulin and Related Proteins Structure to Function and Pharmacology 1st Table of contents:

1. How Insulin Came from Heidelberg to Aachen and Why it Took Five Years (Likely a historical or personal account of research)
2. Insulin at the German Wool Research Institute - Retrospect and Outlook (Potentially discussing early research and developments)
3. Insulin: Sequence, Structure and Function - A Story of Surprises (A foundational chapter on the molecule's basic characteristics and unexpected findings)
4. The Association/Dissociation Equilibria of Insulin in the Presence of Metal Ions: A Fluorescence Energy Transfer and Circular Dichroism Study (Focus on biophysical properties and techniques)
5. Self-Association of Insulin Reconsidered (Further in-depth analysis of insulin's aggregation states)
6. T-R Transition (Referring to the T-state and R-state conformations of insulin, crucial for receptor binding)
7. Comparison of Conformational Transitions in Proteins (Broader context of protein dynamics with insulin as a key example)
8. Activities of Insulin Analogues at Position A8 are Uncorrelated with Thermodynamic Stability (Detailed study on specific amino acid modifications and their impact)
9. Relationships between the Structure of Insulin and its Physiological Effects (Connecting molecular structure to biological function)
10. Structure-Function Relationships of Insulin and Insulin-Like Growth Factor-I Receptor Binding (Exploring the interaction of insulin and related proteins with their receptors)
11. Structural Relationships between Members of the Insulin Receptor Family (Comparative analysis of related receptor structures)
12. Insulin Interaction with Minimized Receptors and Binding Proteins (Studies using simplified receptor models)
13. Identification of Susceptibility Loci for Obesity, Insulin Resistance, and Hyperglycemia in a Backcross Model of New Zealand Obese (NZO) and Lean SJL Mice (Animal model studies in metabolic diseases
14. Activation Mechanism of Fibroblast Growth Factor Receptor Tyrosine Kinase Revealed by Crystal Structure of Fibroblast Growth Factor Receptor Ectodomain Bound to Fibroblast Growth Factor and Heparin (While not directly about insulin, likely included to provide context on related receptor signaling or structural biology techniques
15. IL-6 Type Cytokine Receptor Complexes (Another chapter potentially broadening the scope to related signaling pathways or protein-receptor interactions)
16. Inhibition of Growth Factor Stimulated Pathways for the Treatment of Prostate Cancer (A more applied/pharmacological chapter on targeting signaling pathways)
17. Molecular Dynamics Simulations of Carbonmonoxy Myoglobin and Calculations of Heme Circular Dichroism (A methodological chapter on computational biology applied to proteins, possibly illustrating techniques relevant to insulin research)

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Tags: Matthias Federwisch, Markus Leyck Dieken, Pierre De Meyts, Insulin, Pharmacology