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76 reviewsrent era have been widely depicted in epidemiological studies. Its treatment is codified and relies on medical care
and extracorporeal life support (ECLS) in the bridge to recovery, chronic mechanical device therapy, or trans-
plantation. Recent improvements have changed the landscape of CS. The present analysis aims to review current
medical treatments of CS in light of recent literature, including addressing excitation–contraction coupling and
specific physiology on applied hemodynamics. Inotropism, vasopressor use, and immunomodulation are discussed
as pre-clinical and clinical studies have focused on new therapeutic options to improve patient outcomes. Certain
underlying conditions of CS, such as hypertrophic or Takotsubo cardiomyopathy, warrant specifically tailored
management that will be overviewed in this review.
