Locoregional Tumor Therapy 1st Edition Eric Van Cutsem Thomas J Vogl by Eric Van Cutsem, Thomas J. Vogl, Franco Orsi, Alberto Sobrero (eds.) 9783642365713, 364236571X instant download after payment.

Recent years have witnessed a renaissance in the use of locoregional tumor therapy as part of a multimodal therapeutic approach to a variety of solid tumors, and attempts are underway to define its value in the overall therapeutic strategy for individual tumor entities. This flourishing of interest in locoregional tumor therapy derives from a series of important new developments concerning methodology, drug treatments, and instrumentation. The resulting approaches include not only optimized locoregional chemotherapy and chemoembolization for hepatocellular carcinoma and other tumors, but also other “targeted” therapies such as stereotactic radiosurgery, radiofrequency ablation, intra-arterial administration of radiopharmaceuticals, and complex new methods of chemoembolization of liver metastases involving the use of multiagent chemotherapy in combination with targeted drugs, drug-eluting beads/microspheres, or nanoparticles. In addition, intraperitoneal and intrapleural therapies, e.g., cytoreduction plus hyperthermic intraperitoneal chemotherapy, are now a standard element of the strategy for a range of tumors. It is vital that practitioners have the necessary expertise in the use of these locoregional treatment methods and understand how to combine them optimally with modern systemic therapies. With that goal in mind, this book presents, in condensed form, the clinical results achieved using various locoregional tumor therapies. In so doing, it will allow the reader to rapidly retrieve the information on indications and effectiveness that is required for optimal integration of these highly effective therapies into modern, yet more complex treatment strategies.
近年来，局部肿瘤疗法作为各种实体瘤的多模式治疗方法的一部分，正在尝试定义其在单个肿瘤实体的整体治疗策略中的价值。这种对局部肿瘤治疗兴趣的蓬勃发展源于一系列关于方法学、药物治疗和仪器的重要新发展。由此产生的方法不仅包括针对肝细胞癌和其他肿瘤的优化局部化疗和化疗栓塞，还包括其他“靶向”疗法，如立体定向放射外科手术、射频消融、放射性药物的动脉内给药，以及涉及使用多药化疗联合靶向药物、药物洗脱珠/微球或纳米颗粒的复杂肝转移化疗新方法。此外，腹腔内和胸膜内治疗，例如细胞减灭术加热灌注腹腔内化疗，现在是一系列肿瘤策略的标准要素。至关重要的是，从业者必须具备使用这些局部治疗方法的必要专业知识，并了解如何将它们与现代全身疗法最佳