Lysosomes Biology Diseases And Therapeutics Maxfield Frederickwillard by Maxfield, Frederick;willard, James;lu, Shuyan 9781118645154, 9781118978306, 9781118978313, 1118645154, 1118978307, 1118978315 instant download after payment.

This up-to-date, comprehensive book about lysosomes discusses their functions, properties, and roles in disease, drug development, and therapeutics. Pulling together perspectives from various fields, like toxicology, biology, and pharmacology, this book illustrates the potential of lysosomes beyond their cellular function, focusing on disease and drug targeting. The book is divided into two sections. The first section, "Lysosomes, New Roles, and Link with Diseases" covers basics, fundamentals, and physiological processes. It includes chapters on the lysosome's role in therapeutic pathways, cancer, cell death, and metabolism. The second section, "Lysosome and Drug Development" explores lysosomes in various aspects of drug development and toxicity. Chapters discuss cancer cell resistence, ADC delivery and efficacy, drug-induced toxicity, and pharmacokinetics by lysosomes. Incorporating a broad range of information, strategies, mechanisms, and novel discoveries in the field, this book integrates key aspects of lysosomes to present an understanding of their roles, potential, and future prospects.