Managing Hypertension In Older Adults Brent M Egan Holly J Mattixkramer Jan N Basile Susan E Sutherland by Brent M. Egan & Holly J. Mattix-kramer & Jan N. Basile & Susan E. Sutherland instant download after payment.

Abstract

Purpose of Review The population of older adults 60–79 years globally is projected to double from 800 million to 1.6 billion between 2015 and 2050, while adults≥80 years were forecast to more than triple from 125 to 430 million. The risk

for cardiovascular events doubles with each decade of aging and each 20 mmHg increase of systolic blood pressure. Thus,

successful management of hypertension in older adults is critical in mitigating the projected global health and economic

burden of cardiovascular disease.

Recent Findings Women live longer than men, yet with aging systolic blood pressure and prevalent hypertension increase

more, and hypertension control decreases more than in men, i.e., hypertension in older adults is disproportionately a women’s

health issue. Among older adults who are healthy to mildly frail, the absolute benefit of hypertension control, including

more intensive control, on cardiovascular events is greater in adults≥80 than 60–79 years old. The absolute rate of serious

adverse events during antihypertensive therapy is greater in adults≥80 years older than 60–79 years, yet the excess adverse

event rate with intensive versus standard care is only moderately increased. Among adults≥80 years, benefits of more

intensive therapy appear non-existent to reversed with moderate to marked frailty and when cognitive function is less than

roughly the twenty-fifth percentile. Accordingly, assessment of functional and cognitive status is important in setting blood

pressure targets in older adults.