New Therapeutic Strategies For Type 2 Diabetes Small Molecule Approaches Robert M Jones by Robert M Jones 9781849734141, 9781849735322, 1849734143, 1849735328 instant download after payment.

Content: Preface, Type 2 Diabetes - Disease Overview; Marketed Small Molecule Dipeptidyl Peptidase IV (DPP4) Inhibitors as a New Class of Oral Anti-diabetics; SGLT2 Inhibitors in Development; Glucokinase Activators in Development; 11 -Hydroxysteroid dehydrogenase type 1 (11 -HSD1) inhibitors in development; Recent Advances in PTP1B Inhibitor Development for the Treatment of Type-2 Diabetes and Obesity; Recent advances in the discovery of GPR119 agonists; Acyl-CoA:diacylglycerol acyltransferase-1 inhibition as an approach to the treatment of type 2 diabetes; Stearoyl-CoA Desaturase 1 (SCD1) Inhibitors: Bench to Bedside Must Only Go through Liver; TGR5 Agonists in Development; The discovery and development of MB07803, a second generation fructose-1,6-bisphosphatase inhibitor with improved pharmacokinetic properties, as a potential treatment of type 2 diabetes; Inhibition of Glycogen Phosphorylase as a Strategy for the Treatment of Type 2 Diabetes; SIRT1 Activators in Development; Long-Chain Free Fatty Acid Receptor Agonists; Glucagon Receptor Antagonists in Development; ACC Inhibitors in Development; Index