Nextgeneration Nanobiosensor Devices For Pointofcare Diagnostics Gorachand Dutta by Gorachand Dutta 9789811971297, 9811971293 instant download after payment.

Rapid detection and point-of-care (POC) diagnostics have become very crucial especially after the life-threatening corona virus pandemic. The pandemic has proved that despite tremendous advances in medical sciences and technology, sorely we are lagging in health care research. Detection schemes can be realized with an electro-chemical platform, thanks to its promising advantages like low-to-moderate cost, high sensitivity, and selectivity with a lower limit of detection (LOD), rapid response, and easy integration with microfluidic systems. A variety of signal amplification methods based on electrochemical-chemical-chemical (ECC) redoxcycling and rolling circle amplification (RCA) have been explored. Integration of these systems opens a new horizon to fabricate miniaturized devices, disposability, need for less sample volume, multiplex, and POC sensing ability.
Our motto is to fabricate a label-free, wash-free, and portable electrochemical biosensor for point-of-care application and early detection of disease. It will be in the form of a handheld or bench-top instrument which will accept a sample with very little or no prepreparation and can provide a comprehensible result in seconds to hours for easy interpretation. Next-Generation Nanobiosensor Devices for Point-of-Care Diagnostics was prepared for beginning and experienced authors to explore the challenges for the development of next-generation point-of-care test platform using nanobiotechnology. In this book, we address these challenges for the development of a point-of-care test platform. The book also describes printed chip-based assays (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive, biomarkers detection in real samples.The main challenges of point-of-care testing require implementing complex analytical methods into low-cost technologies.