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90 reviewsmanagement of decompensated cirrhotic patients, so we focused this review on improving care for
compensated cirrhotic patients who are followed up in outpatient clinics.
Areas covered: We reviewed the current methods for establishing liver function, the diagnosis and
management of advanced chronic liver disease and clinically significant portal hypertension as well as
the prevention of its complications, with special attention to covert hepatic encephalopathy, we also
paid attention to the extrahepatic complications of cirrhosis and the palliative care. All this from the
perspective of evidence-based medicine and trying to empower precision medicine. The literature
search was undertaken by PubMed with ‘cirrhosis,’ ‘advanced chronic liver disease,’ ‘liver function,’
‘portal hypertension,’ ‘covert hepatic encephalopathy,’ ‘minimal hepatic encephalopathy,’ ‘palliative
care’ as MeSH terms.
Expert opinion: We must offer compensated cirrhotic patients specific care and measures to prevent
the progression of the disease and the appearance of its complications beyond the calculation of liver
function and imaging screening for hepatocellular carcinoma that we perform every six months. Entities
that have typically received little attention, such as covert hepatic encephalopathy, extrahepatic
complications and symptoms of cirrhosis, and palliative care, must come to the spotlight.