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Oncogenes Meet Metabolism From Deregulated Genes To A Broader Understanding Of Tumour Physiology Ernst Schering Foundation Symposium Proceedings 074 1st Edition Guido Kroemer

  • SKU: BELL-2204488
Oncogenes Meet Metabolism From Deregulated Genes To A Broader Understanding Of Tumour Physiology Ernst Schering Foundation Symposium Proceedings 074 1st Edition Guido Kroemer
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Oncogenes Meet Metabolism From Deregulated Genes To A Broader Understanding Of Tumour Physiology Ernst Schering Foundation Symposium Proceedings 074 1st Edition Guido Kroemer instant download after payment.

Publisher: Springer
File Extension: PDF
File size: 3.89 MB
Pages: 275
Author: Guido Kroemer, Dominik Mumberg, Hector Keun, Björn Riefke, Thomas Steger-Hartmann, Kirstin Petersen
ISBN: 9783540794776, 9783540794783
Language: English
Year: 2008
Edition: 1

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Oncogenes Meet Metabolism From Deregulated Genes To A Broader Understanding Of Tumour Physiology Ernst Schering Foundation Symposium Proceedings 074 1st Edition Guido Kroemer by Guido Kroemer, Dominik Mumberg, Hector Keun, Björn Riefke, Thomas Steger-hartmann, Kirstin Petersen 9783540794776, 9783540794783 instant download after payment.

In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg’s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effects on metabolism with the help of modern analytic technologies to rapidly analyze broad varieties of metabolites in various tissues and bodyfluids (metabonomics).

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