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4.7
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ISBN 10: 0124708625
ISBN 13: 9780124708624
Author: Robert Marcus; David Feldman; Jennifer L. Kelsey
Osteoporosis is the most comprehensive, authoritative reference on this disease. Some of the topics covered include basic biology, anatomy, physiology, pathophysiology, preclinical issues, experimental medicine, management, and therapeutics. Written by renowned experts in this field, this book is a must-have for the researcher, the academic clinician, or anyone in the field of bone biology.
Key Features
* The source on osteoporosis
* Written by expert investigators in their respective fields
* Each chapter provides timely, comprehensive, and scholarly discussion
* Fully illustrated in color and black & white
* Covers everything from basic anatomy and physiology to diagnosis, management and treatment
Part I: Introduction to Normal Bone Physiology and Pathophysiology
The Bone Organ System: Form and Function
Osteoblast Biology
Osteoclast Biology
The Biochemistry of Bone
Developmental Biology of Bone
Mouse Genetics as a Tool to Study Bone Development and Physiology
Parathyroid Hormone and Parathyroid Hormone-Related Protein
Calcitonin
Vitamin D: Biology, Action, and Clinical Implications
Regulation of Bone Cell Function by Estrogens
Skeletal Biology of Androgens
Coupling of Bone Resorption and Formation during Bone Remodeling
Cytokines and Bone Remodeling
Bone Growth Factors
Skeletal Heterogeneity and the Purposes of Bone Remodeling
Basic Biology of Bisphosphonates
Part II: Structure and Biomechanics
17. Skeletal Development: Mechanical Consequences of Growth, Aging, and Disease
18. Inhibition of Osteopenia by Biophysical Intervention
19. Biomechanics of Age-Related Fractures
Part III: Epidemiology and Risk Factors
20. Introduction to Epidemiologic Methods
21. Magnitude and Impact of Osteoporosis and Fractures
22. Race, Ethnicity, and Osteoporosis
23. Epidemiology of Osteoporotic Fractures in Europe
24. Bone Mineral Acquisition in Utero, during Infancy, and throughout Childhood
25. Bone Acquisition in Adolescence
26. Genetics and Genomics of Osteoporosis
27. Nutrition and Risk for Osteoporosis
28. Physical Activity and Osteoporosis
29. Premenopausal Reproductive and Hormonal Characteristics and the Risk for Osteoporosis
30. Postmenopausal Endogenous and Exogenous Hormones, Degree of Obesity, Thiazide Diuretics
31. The Effects of Tobacco and Alcohol Use on Bone
32. Falls as Risk Factors for Fractures
33. Assessing Fracture Risk
34. Outcomes of Osteoporotic Fractures
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Tags: Robert Marcus, David Feldman, Jennifer Kelsey, Osteoporosis