Practical Methods For Biocatalysis And Biotransformations 2 John Whittall by John Whittall, Peter W. Sutton 9781119943426, 9781119991397, 1119943426, 1119991390 instant download after payment.
Biocatalysts are increasingly used by chemists engaged in fine chemical synthesis within both industry and academia. Today, there exists a huge choice of high-tech enzymes and whole cell biocatalysts, which add enormously to the repertoire of synthetic possibilities.
Practical Methods for Biocatalysis and Biotransformations 2 is a "how-to" guide that focuses on the practical applications of enzymes and strains of microorganisms that are readily obtained or derived from culture collections. The sources of starting materials and reagents, hints, tips and safety advice (where appropriate) are given to ensure, as far as possible, that the procedures are reproducible. Comparisons to alternative methodology are given and relevant references to the primary literature are cited. This second volume – which can be used on its own or in combination with the first volume - concentrates on new applications and new enzyme families reported since the first volume. Contents include:
- introduction to recent developments and future needs in biocatalysts and synthetic biology in industry
- reductive amination
- enoate reductases for reduction of electron deficient alkenes
- industrial carbonyl reduction
- regio- and stereo- selective hydroxylation
- oxidation of alcohols
- selective oxidation
- industrial hydrolases and related enzymes
- transferases for alkylation, glycosylation and phosphorylation
- C-C bond formation and decarboxylation
- halogenation/dehalogenation/heteroatom oxidation
- tandem and sequential multi-enzymatic syntheses
Practical Methods for Biocatalysis and Biotransformations 2 is an essential collection of biocatalytic methods for chemical synthesis which will find a place on the bookshelves of synthetic organic chemists, pharmaceutical chemists, and process R&D chemists in industry and academia.
Content:
Chapter 1 Biocatalysis in the Fine Chemical and Pharmaceutical Industries (pages 1–59): Peter W. Sutton, Joseph P. Adams, Ian Archer, Daniel Auriol, Manuela Avi, Cecilia Branneby, Andrew J. Collis, Bruno Dumas, Thomas Eckrich, Ian Fotheringham, Rob ter Halle, Steven Hanlon, Marvin Hansen, K. E. Holt?Tiffin, Roger M. Howard, Gjalt W. Huisman, Hans Iding, Kurt Kiewel, Matthias Kittelmann, Ernst Kupfer, Kurt Laumen, Fabrice Lefevre, Stephan Luetz, David P. Mangan, Van A. Martin, Hans?Peter Meyer, Thomas S. Moody, Antonio Osorio?Lozada, Karen Robins, Radka Snajdrova, Matthew D. Truppo, Andrew Wells, Beat Wirz and John W. Wong
Chapter 2 Reductive Amination (pages 61–86): Simon Willies, Matthew D. Truppo, Christopher K. Savile, Jacob M. Janey, Jeffrey C. Moore, Gjalt W. Huisman, Gregory J. Hughes, Francesco G. Mutti, Christine S. Fuchs, Wolfgang Kroutil, Jennifer Hopwood, Matthew D. Truppo, Richard Lloyd, Nicholas J. Turner, Eun Young Hong, Minho Cha, Hyungdon Yun, Byung?Gee Kim, S. Stella and Anju Chadha
Chapter 3 Enoate Reductases for Reduction of Electron Deficient Alkenes (pages 87–114): Melanie Hall, Christoph K. Winkler, Gabor Tasnadi, Kurt Faber, Elisabetta Brenna, Francesco G. Gatti, Fabio Parmeggiani, Pietro Buzzini, Marta Goretti, Chiara Ponzoni, Elisa Caselli, Eva Branda, Maria Rita Cramarossa, Benedetta Turchetti, Luca Forti, Adam Z. Walton, Bradford T. Sullivan, Jon D. Stewart, Maximiliano A. Sortino and Susana A. Zacchino
Chapter 4 Industrial Carbonyl Reduction (pages 115–127): David P. Mangan, Thomas S. Moody, Owen Gooding, Gjalt W. Huisman, Carlos A. Martinez, Adam Smogowicz, Jeremy S. Steflik, Maria S. Brown, Katarina S. Midelfort, Michael P. Burns, John W. Wong and Jack Liang
Chapter 5 Regio? and Stereoselective Hydroxylation (pages 129–162): Marcus Hans, Jan?Metske van der Laan, Ben Meijrink, Wibo van Scheppingen, Richard Kerkman, Marco van den Berg, Matthias Kittelmann, Anton Kuhn, Annina Riepp, Jurgen Kuhnol, Andreas Fredenhagen, Lukas Oberer, Oreste Ghisalba, Stephan Luetz, David P. Mangan, Thomas S. Moody, David Schmid, Antonio Osorio?Lozada, F. Ozde. Utkur, Jonathan Collins, Christoph Brandenbusch, Gabriele Sadowski, Andreas Schmid, Bruno Buhler, Matthias Kinne, Marzena Poraj?Kobielska, Rene Ullrich, Martin Hofrichter, Gideon Grogan and Mark L. Thompson
Chapter 6 Oxidation of Alcohols (pages 163–179): Rajesh Kumar, Jim Cawley, Michael Karmilowicz, Carlos A. Martinez, Nathan Wymer, Bo Yuan, Franck Escalettes, Nicholas J. Turner, Johann H. Sattler, Katharina Tauber, Francesco G. Mutti and Wolfgang Kroutil
Chapter 7 Selective Oxidation (pages 181–202): Valentin Kohler, Bas Groenendaal, Kevin R. Bailey, Anass Znabet, James Raferty, Madeleine Helliwell, Nicholas J. Turner, Kristian Geitner, Uwe T. Bornscheuer, Gonzalo de Gonzalo, Vicente Gotor, Shuvendu Das, John P. N. Rosazza, Aashrita Rajagopalan, Francesco G. Mutti and Wolfgang Kroutil
Chapter 8 Industrial Hydrolases and Related Enzymes (pages 203–229): Mark Dow, Rebecca Meadows, Rhona Sinclair, Andrew Wells, Gary Breen, John Carey, Fiona Rawlinson, K. E. Holt?tiffin, M. C. Lloyd, Beat Wirz, Paul Spurr, Christophe Pfleger, Graham Checksfield, Stewart T. Hayes, Wilfried Hoffmann, Christian T. Regius, Gemma Scotney, Sarah L. Spencer, Roger M. Howard, Colin M. Burns, Gordon B. Ward, Robert Walton, Neil Barnwell, Matthew D. Truppo and Gregory J. Hughes
Chapter 9 Transferases for Alkylation, Glycosylation and Phosphorylation (pages 231–262): Daniel Auriol, Rob ter Halle, Fabrice Lefevre, Daniel F. Visser, Gregory E. R. Gordon, Moira L. Bode, Kgama Mathiba, Dean Brady, Karel De Winter, Tom Desmet, An Cerdobbel, Wim Soetaert, Teunie van Herk, Aloysius F. Hartog, Ron Wever, Malgorzata Brzezinska?rodak, Magdalena Klimek?Ochab, Ewa Zymanczyk?Duda, Joyeeta Mukherjee, Munishwar N. Gupta, Wen?Bing Yin, Shu?Ming Li and Mandana Gruber?Khadjawi
Chapter 10 C–C Bond Formation and Decarboxylation (pages 263–295): Alessandra Bonamore, Alberto Macone, Wolfgang Kroutil, Birgit Seisser, Tijs M. Lammens, Daniela De Biase, Maurice C. R. Franssen, Elinor L. Scott, Johan P. M. Sanders, Kenji Miyamoto, Robert Kourist, Shosuke Yoshida, Hiromichi Ohta, Jie Tian, Heng Li, Wen?Yun Gao, Saravanakumar Shanmuganathan, Dessy Natalia, Lasse Greiner, Pablo Dominguez de Maria, Yan?Hong He, Zhi Guan and Jian?Feng Cai
Chapter 11 Halogenation/Dehalogenation/Heteroatom Oxidation (pages 297–312): Jia Zeng, Jixun Zhan, Zbynek Prokop, Veronika Stepankova, Khomaini Hasan, Radka Chaloupkova, Jiri Damborsky, Ai?Tao Li, Gao?Wei Zheng, Hui?Lei Yu, Jiang Pan, Chun?Xiu Li, Jian?He Xu, Marian Mikolajczyk, Jerzy luczak and Piotr Kielbasinski
Chapter 12 Tandem and Sequential Multi?Enzymatic Syntheses (pages 313–345): Bong?Gyu Kim, Joong?Hoon Ahn, Guido Sello, Patrizia Di Gennaro, Teunie van Herk, Aloysius F. Hartog, Ron Wever, Isabel Oroz?Guinea, Israel Sanchez?Moreno, Eduardo Garcia?Junceda, Bian Wu, Wiktor Szymanski, Ben L. Feringa, Dick B. Janssen, Ly Villo, Malle Kreen, Marina Kudryashova, Andrus Metsala, Sven Tamp, ulo Lille, Tonis Pehk, Omar Parve, Kathleen McClean and Peter Eddowes
