Principles Of Endocrinology And Hormone Action 1st Antonino Belfiore by Antonino Belfiore, Derek Leroith 9783319446745, 9783319446752, 9783319452173, 3319446746, 3319446754, 3319452177 instant download after payment.

The endocrine system involves a complex signaling network that regulates essential functions involved in growth, reproduction, and homeostasis. We are increasingly recognizing that this regulatory system comprises not only hormones secreted by the classical endocrine glands, but also hormones and regulatory factors produced by
many organs and tissues, such as the heart, gut, bone, and adipose tissue, and that it involves extensive cross talk with the neural and immune system that are the other two crucial regulatory networks. At the same time, our knowledge of hormone synthesis, release, and transport as well as the molecular basis of hormone action has been greatly and rapidly expanded. Endocrine disorders include hormone deficiency or excess as well as peripheral resistance to selective hormones. Some of these disorders, such as thyroid diseases and type 2 diabetes mellitus, represent real social health problems for their high prevalence in the population and severe clinical complications. Several other disorders are less frequent but equally critical for health or otherwise important for their social implications, such as disorders involving impairment of growth or fertility. Emerging aspects include the notion that common endocrine disorders, such as insulin resistance and related conditions, may increase cancer risk and that the endocrine system contributes to regulate the process of
aging.
This volume has the ambitious aims to provide a comprehensive coverage of the current view of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular level. It is intended to provide essential as well as in depth information to the medical students, but also to specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine.