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ISBN 10: 0444560831
ISBN 13: 9780444560834
Author: Jangu Banatvala
This latest volume provides a comprehensive review of the latest developments and research studies on the pathogenesis and molecular biology of human congenital infections. It reviews current diagnostic techniques and epidemiological data while describing the progress in research and understanding of continuing prevention of congenital infections and prognosis.
Chapter 1. Molecular Virology of Rubella Virus
Introduction
Structure of the virion
Genome organization
Attachment and entry
Intracellular site of RNA replication
Transcription and translation
Genome replication
Interactions between rubella virus proteins and cellular proteins involved in cell cycle regulation
Assembly of virions
Molecular epidemiology of rubella
General comments about the molecular virology of rubella virus
References
Chapter 2. Clinical Features: Post-Natally Acquired Rubella
Introduction
Clinical features
Differential diagnosis
Complications
Congenitally acquired infection
References
Chapter 3. Laboratory Diagnosis of Rubella and Congenital Rubella
Introduction
Laboratory techniques
Diagnosis of rubella
Remaining diagnostic problems
Conclusions and outlook
Acknowledgements
References
Chapter 4. Rubella Vaccine
Introduction
Active immunization
Dose and route of administration
Combination of the vaccine
Immune responses
Protective effects and reinfection
Adverse events
Contraindications and precautions
Use of rubella-containing vaccine globally
Cost-effectiveness of rubella-containing vaccines in developing countries
Summary
References
Chapter 5. Rubella Epidemiology: Surveillance to Monitor and Evaluate Congenital Rubella Prevention
Congenital rubella infection
Epidemiological features of the rubella virus
Prevention of congenital rubella
References
Future Requirements
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Tags: Jangu Banatvala, Rubella, Viruses
