Sepsis New Insights New Therapies Novartis Foundation Symposium 280 Novartis Foundationeds by Novartis Foundation(eds.) 9780470027981, 9780470059593, 0470027983, 0470059591 instant download after payment.

• Addresses the frequent, but under-recognised condition of sepsis and discusses new ways to prevent and treat it
• Describes numerous pharmacological approaches to therapy for early and late sepsis
• Includes detailed discussion of the various physiological systems implicated in sepsis
• Presents an international perspective, featuring contributions from experts from laboratories worldwide involved in the study of sepsis

Sepsis: New Insights, New Therapies is an invaluable resource for all critical care physicians and researchers. It is also informative reading for immunologists, endocrinologists, neuroendocrinologists, physiologists, and pharmacologists.Content:
Chapter 1 Chair's Introduction (pages 1–6): Mitchell P. Fink
Chapter 2 Strategies to Modulate Cellular Energetic Metabolism during Sepsis (pages 7–20): Alessandro Protti and Mervyn Singer
Chapter 3 Immunostimulation is a Rational Therapeutic Strategy in Sepsis (pages 21–36): Jerome Pugin
Chapter 4 Blockade of Apoptosis as a Rational Therapeutic Strategy for the Treatment of Sepsis (pages 37–52): Alfred Ayala, Doreen E. Wesche?Soldato, Mario Perl, Joanne L. Lomas?Neira, Ryan Swan and Chun?Shiang Chung
Chapter 5 Modulating Neutrophil Apoptosis (pages 53–72): John C. Marshall, Zeenat Malam and Songhui Jia
Chapter 6 HMGB1 as a Potential Therapeutic Target (pages 73–91): Haichao Wang, Wei Li, Richard Goldstein, Kevin J. Tracey and Andrew E. Sama
Chapter 7 Poly (ADP?Ribose) Polymerase Activation and Circulatory Shock (pages 92–107): Csaba Szabo
Chapter 8 Choosing the Right Substrate (pages 108–127): Xavier Leverve, Cecile Batandier and Eric Fontaine
Chapter 9 Inhibiting Glycogen Synthase Kinase 3? in Sepsis (pages 128–146): Laura Dugo, Marika Collin, David A. Allen, Nimesh S. A. Patel, Inge Bauer, Eero M. A. Mervaala, Marjut Louhelainen, Simon J. Foster, Muhammad M. Yaqoob and Christoph Thiemermann
Chapter 10 Ethyl Pyruvate: A Novel Treatment for Sepsis (pages 147–159): Mitchell P. Fink
Chapter 11 General Discussion I (pages 160–164):
Chapter 12 Cytoprotective and Anti?Inflammatory Actions of Carbon Monoxide in Organ Injury and Sepsis Models (pages 165–181): Stefan W. Ryter and Augustine M. K. Choi
Chapter 13 The Hypothalamic Pituitary Adrenal Axis in Sepsis (pages 182–203): Andrea Polito, Jerome Aboab and Djillali Annane
Chapter 14 Modulating the Endocrine Response in Sepsis: Insulin and Blood Glucose Control (pages 204–222): Ilse Vanhorebeek, Lies Langouche and Greet Van den Berghe
Chapter 15 The Neuronal Strategy for Inflammation (pages 223–237): Luis Ulloa and Ping Wang
Chapter 16 Beta?Blockade in Burns (pages 238–251): C. T. Pereira, M. G. Jeschke and D. N. Herndon
Chapter 17 System Interactions (pages 252–265): Mervyn Singer
Chapter 18 Protecting the Permeability Pore and Mitochondrial Biogenesis (pages 266–280): C. A. Piantadosi, M. S. Carraway, D. W. Haden and H. B. Suliman