Therapeutic Proteins Strategies To Modulate Their Plasma Halflives Roland Kontermann by Roland Kontermann 9783527644780, 9783527644797, 9783527644803, 9783527644827, 3527644784, 3527644792, 3527644806, 3527644822 instant download after payment.

Content: Front Matter --
General Information. Half-Life Modulating Strategies : An Introduction / Roland E Kontermann --
Pharmacokinetics and Half-Life of Protein Therapeutics / Bernd Meibohm --
Half-Life Extension through Chemical and Post-Translational Modifications. Half-Life Extension through PEGylation / Simona Jev₍evar, Menci Kunstelj --
Half-Life Extension of Therapeutic Proteins via Genetic Fusion to Recombinant PEG Mimetics / Uli Binder, Arne Skerra --
Half-Life Extension through -Glycosylation / Fuad Fares --
Polysialic Acid and Polysialylation to Modulate Antibody Pharmacokinetics / Antony Constantinou, Chen Chen, Mahendra P Deonarain --
Half-Life Extension through HESylationʼ / Thomas Hey, Helmut Knoller, Peter Vorstheim --
Half-Life Modulation Involving Recycling by the Neonatal Fc Receptor. The Biology of the Neonatal Fc Receptor (FcRn) / Jonghan Kim --
Half-Life Extension by Fusion to the Fc Region / Jalal A Jazayeri, Graeme J Carroll --
Monomeric Fc Fusion Technology: An Approach to Create Long-Lasting Clotting Factors / Jennifer A Dumont, Xiaomei Jin, Robert T Peters, Alvin Luk, Glenn F Pierce, Alan J Bitonti --
The Diverse Roles of FcRn: Implications for Antibody Engineering / E Sally Ward, Raimund J Ober --
Half-Life Extension by Fusion to Recombinant Albumin / Hubert J Metzner, Thomas Weimer, Stefan Schulte --
AlbudAb₉ Technology Platform₆Versatile Albumin Binding Domains for the Development of Therapeutics with Tunable Half-Lives / Christopher Herring, Oliver Schon --
Half-Life Extension by Binding to Albumin through an Albumin Binding Domain / Fredrik Y Frejd --
Half-Life Extension by Binding to Albumin through Small Molecules / Sabrina Trussel, Joerg Scheuermann, Dario Neri --
Half-Life Extension with Pharmaceutical Formulations. Half-Life Extension with Pharmaceutical Formulations: Liposomes / Astrid Hartung, Gerd Bendas --
Half-Life Extension with Pharmaceutical Formulations: Nanoparticles by the Miniemulsion Process / Katharina Landfester, Anna Musyanovych, Volker Mail̃nder --
Index.