Towards Efficient Designing Of Safe Nanomaterials Innovative Merge Of Computational Approaches And Experimental Techniques Jerzy Leszczynski by Jerzy Leszczynski, Tomasz Puzyn 9781849734530, 9781849735476, 1849734534, 1849735476 instant download after payment.

The expanding field of nanotechnology is now one of the most promising areas of science. However, because some nanoparticles can have a negative impact on human health and the environment, the design of novel materials must always be accompanied by a comprehensive risk assessment. Until now, the information on the methods available has been fragmented and incomplete. This book is the first to provide a comprehensive review of recent progress and challenges in the risk assessment of nanomaterials by empirical and computational techniques.Topics covered include: benefits versus risks, carbon based nanomaterials, environmental detection and quantitative analysis, chemometric modelling, human exposure assessment, toxicity testing, nano-QSAR, risk assessment strategies, policy and regulatory frameworks. Read more... Content: Nanomaterials: benefits and risks; Experimental characterizing structural properties of nanoparticles related to their toxicity; Structure-property mapping methods; Modelling properties of nanoparticles based on quantum-mechanical methods; Ontology; Empirical determination of nanoparticles' behavior in environmental media; Computational mass-ballance modeling of environmental transport and fate of engineered nanoparticles; Pharmacokinetics and biological fate of nanoparticles; Pharmacokinetic-based modeling; Modeling kinetics of nanoparticle cellular interaction and transport; Toxicity and Ecotoxicity testing of engineered nanoparticles - experimental point of view; In vitro toxicity of nanomaterials; In vivo testing; Computational modeling of interactions between nanoparticles and other species; Comprehensive Environmental Assessment as a Tool for Nanomaterial Risk Assessment; Predicting oxidative stress; Nano-QSAR Abstract: This book is the first to provide a comprehensive review of recent progress and challenges in the risk assessment of nanomaterials by empirical and computational techniques. Read more...