Vitamins and Hormones 62 1st Edition by Gerald Litwack ISBN 0127098623 978-0127098623 by Gerald Litwack 9780127098623, 0127098623 instant download after payment.

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Product details:

ISBN 10: 0127098623 

ISBN 13: 978-0127098623

Author: Gerald Litwack

Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board reflects expertise in the fields of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Every volume contains comprehensive reviews by leading contributors.

Table of contents:

Chapter 1. Green Tea: Biochemical and Biological Basis for Health Benefits
I. Introduction
II. Catechins and Other Constituents of Green Tea
III. Structure, Pharmacology, and Metabolism of Catechins
IV. Chemical and Biochemical Properties of Catechins
V. Biological Activity of Green Tea Catechins
VI. Molecular and Cellular Bases for Biological Effects of Catechins
VII. Epilog
References

Chapter 2. Proteins Regulating the Biosynthesis and Inactivation of Neuromodulatory Fatty Acid Amide
I. Fatty Acid Amides as Endogenous Signaling Molecules
II. The Biosynthesis of Fatty Acid Amides
III. The Enzymatic Inactivation of Fatty Acid Amides
IV. Transport of Fatty Acid Amides
V. Conclusions and Future Challenges
References

Chapter 3. Three-Dimensional Organization of the Aquaporin Water Channel: What Can Structure Tell Us
I. Movement of Water across the Membrane, Discovery of Aquaporin-1
II. Mammalian Aquaporins and Their Transport Function
III. Investigations of Amino Acid Residues Involved in Solute Transport in Aquaporins
IV. Structural Studies of Aquaporins
V. Unresolved Questions and Future Directions
References

Chapter 4. Cytostatic p21 G Protein-Activated Protein Kinase γ-PAK
I. Background
II. Comparison of PAK Proteins
III. Autophosphorylation and Activation of γ-PAK
IV. γ-PAK Has Cytostatic Activity
V. Activation of γ-PAK in Response to Stress
VI. The Individual Roles of γ-PAK and SAPK/p38 in the Stress Response
VII. Substrates for γ-PAK
VIII. Working Model—A Role for γ-PAK as a Master Switch
IX. Conclusions and Remaining Questions
References

Chapter 5. Androgen Receptors and Their Biology
I. Mechanism of Androgen Action
II. Sexual Development
III. Androgen Receptors and Disease
IV. Androgen Action and Other Diseases
V. Conclusion
References

Chapter 6. Transcriptional Activation of Genes by 17β-Estradiol through Estrogen Receptor–Sp1 Int
I. Introduction
II. Transcriptional Activation through Sp1(N)xERE 1/2 and Sp1(N)xERE Motifs
III. Transcriptional Activation by E2 through GC-Rich Sites
IV. E2-Responsive Genes with Functional GC-Rich Promoter Elements
V. ERα/Sp1 Activation by Growth Factors
VI. ERα/Sp1 vs ERβ/Sp1 Action and Effects of Ligand Structure and Cell Context
VII. Summary
References

Chapter 7. Drug Discovery and the Intracellular Receptor Family
I. The History of Intracellular Receptor Ligands as Drugs
II. Diseases in Which Intracellular Receptors Play a Role
III. Intracellular Receptor Ligands with Therapeutic Utility (Agonists and Antagonists)
IV. Partial Agonists of Intracellular Receptors
V. Ligand Discovery
VI. Direct Measures of Intracellular Receptor Conformation
VII. Indirect Methods of Conformation Determination
VIII. Cofactor–Receptor Interactions
IX. Assays Used to Measure the Function of the Ligand–Receptor Complex
X. The in Vitro–in Vivo Connection
XI. Conclusion
References

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