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0 reviewsf oa b s t r a c tArticle history:In this perspective, we introduce the concept of Symbiopersonal Intelligence (SymAI)—a specialized form ofReceived 30 September 2024artificial intelligence designed to facilitate and optimize symbiotic interactions between individuals and intelliReceived in revised form 14 January 2025gent devices in digital medicine. SymAI represents a new frontier in personalized intelligent systems, adaptivelyAccepted 22 January 2025learning from and catering to individual needs and behaviors. We explore its emergence and potential implemenAvailable online 23 January 2025tation in both personal and public healthcare, encompassing telemedicine, precision medicine, surgical assistance,Keywords:chronic disease management, and policy optimization. Key technological frameworks and hardware enablers areoutlined, with a particular emphasis on multimodal data retrieval, transmission, and processing, as well as perArtificial intelligencesonalized interventions delivered via wearable and implantable devices. By integrating artificial intelligence intoHealthcaresensor technologies and addressing barriers in flexible electronics, SymAI holds the potential to revolutionizeWearable devicesdigital health, offering more responsive, tailored care and improved health outcomes.Implantable devicesFlexible electronicsAdvanced materials
