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Camptothecins In Cancer Therapy Cancer Drug Discovery And Development 1st Edition Val R Adams

  • SKU: BELL-2526200
Camptothecins In Cancer Therapy Cancer Drug Discovery And Development 1st Edition Val R Adams
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Camptothecins In Cancer Therapy Cancer Drug Discovery And Development 1st Edition Val R Adams instant download after payment.

Publisher: Humana Press
File Extension: PDF
File size: 3.46 MB
Pages: 474
Author: Val R. Adams
ISBN: 1588290271
Language: English
Year: 2005
Edition: 1

Product desciption

Camptothecins In Cancer Therapy Cancer Drug Discovery And Development 1st Edition Val R Adams by Val R. Adams 1588290271 instant download after payment.

A critical review our current understanding of camptothecins, their shortcomings, and of the possibilities for improving their clinical performance. The authors discuss new camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Additional chapters describe what is known about the biochemistry, the pharmacology, and the chemistry of the camptothecins, including the mechanism of topoisomerase and how camptothecins poison this enzyme, the use of animal models in defining the anticancer potential of camptothecins, and the question of camptothecin resistance.

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