International Review of Neurobiology 63 1st Edition by Ronald Bradley, Adron Harris, Peter Jenner ISBN 0080458311 9780080458311 by Ronald J. Bradley, Adron R. Harris, Peter Jenner 9780080458311, 9780123668646 instant download after payment.

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Product details:

ISBN 10: 0080458311
ISBN 13: 9780080458311
Author: Ronald Bradley, Adron Harris, Peter Jenner

Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research.

Table of contents:

MAPPING NEURORECEPTORS AT WORK: ON THE DEFINITION AND INTERPRETATION OF BINDING POTENTIALS AFTER 20

I. Twenty Years of Progress

II. Remaining Issues

III. Solutions

References 1

MITOCHONDRIAL DYSFUNCTION IN BIPOLAR DISORDER: FROM MAGNETIC RESONANCE SPECTROSCOPIC FINDINGS TO THE

I. Introduction 2

II. Phosphorus-31 Magnetic Resonance Spectroscopy

III. Near-Infrared Spectroscopy

IV. Molecular Genetic Findings

V. Roles of Mitochondrial Calcium Regulation

VI. Conclusions

References 2

LARGE-SCALE MICROARRAY STUDIES OF GENE EXPRESSION IN MULTIPLE REGIONS OF THE BRAIN IN SCHIZOPHRENIA

I. Introduction 3

II. Gene Expression Profiling Using Microarrays: Technologies Overview

III. Postmortem Brains and Gene Expression Studies

IV. Comparison of Gene Expression Profiles among Normal Brain Regions

V. Gene Expression Profiles of Brain Regions in Alzheimer’s Disease

VI. Gene Expression Profiling in Schizophrenia

VII. Future Perspectives

References 3

REGULATION OF SEROTONIN 2C RECEPTOR PRE-mRNA EDITING BY SEROTONIN

I. Introduction 4

II. Modification of RNA Sequences by RNA Editing via Hydrolytic Deaminations of Adenosines

III. Enzymes Responsible for A-to-I Editing and Their Substrate Requirements

IV. A-to-I Editing of the 5- HT2C Receptor Pre- mRNA

V. Modulation of 5- HT2C Receptor Function by RNA Editing

VI. 5- HT2C Pre- mRNA Editing Responses to Sustained Changes of Postsynaptic 5-HT2C Receptor Activat

VII. 5- HT2C Pre- mRNA Editing in the Human Prefrontal Cortex and Alterations in Editing-Site Prefer

VIII. Conclusions and Future Directions

References 4

THE DOPAMINE HYPOTHESIS OF DRUG ADDICTION: HYPODOPAMINERGIC STATE

I. Drug Addiction as a Brain Disease

II. The Mesolimbic Dopamine System

III. Behavioral Animal Models

IV. Biochemical Studies

V. Primate Studies

VI. Conclusions

Acknowledgments 5

References 5

HUMAN AND ANIMAL SPONGIFORM ENCEPHALOPATHIES ARE AUTOIMMUNE DISEASES: A NOVEL THEORY AND ITS SUPPORT

I. Introduction 6

II. A New Theory on the Mechanism of Pathogenesis of Spongiform Encephalopathies (SEs)

III. Supporting Evidence

IV. Early Diagnosis, Treatment, and Prevention of Various SE Diseases

V. Conclusions

Acknowledgments 6

References 6

ADENOSINE AND BRAIN FUNCTION

I. Introduction 7

II. Regulation of Brain Adenosine Levels in the Central Nervous System

III. Adenosine Receptors

IV. Functions of Adenosine Receptors

V. Adenosine–Dopamine Interactions in Brain

VI. Phenotypes of Knockout Mice

VII. Adenosine Receptors and Protection against Ischemic and Excitotoxic Brain Injuries

VIII. Adenosine A2A Receptors and Neurodegenerative Disorders

IX. Adenosine Receptors and Psychiatric Disorders

X. Adenosine and the Regulation of Sleep– Wake Cycles

XI. Adenosine and Epilepsy

XII. Adenosine and Pain

Acknowledgments 7

References 7

Index

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